Wang Xiahong, Li Zhenyu, Berglass Jacqueline, He Wenlong, Zhao Jianmin, Zhang Min, Gao Chongyang, Zhang Caixia, Zhang Huimin, Yi Xuewei
Department of Neurology, The Second People's Hospital of Zhengzhou, Zhengzhou, Henan, China.
Department of Neurology, Xinxiang Central hospital, Xinxiang, Henan, China.
Pak J Pharm Sci. 2016 Nov;29(6 Suppl):2317-2320.
To explore the relationship between the clinical manifestations and functional magnetic resonance images of delayed encephalopathy after carbon monoxide intoxication. Six patients received the MRI were diagnosed with delayed encephalopathy after carbon monoxide (CO) poisoning. Clinical manifestations were observed in each patient. MRI revealed multiple lesions. The majority of the lesions were located in the globus pallidus, sub cortical white matter, and basal ganglia. The cognitive injury, akinetic mutism, fecal and uroclepsia, forced crying, forced laughing and extra pyramidal syndromes such as chorea and parkinsonism were manifested in clinic. Cognitive impairment improved greatly while involuntary movements only improved slightly after several months. Meanwhile brain MRI suggested remarkable improvement. Neuroimaging directly correlated with the clinical manifestations.
探讨一氧化碳中毒后迟发性脑病的临床表现与功能磁共振成像之间的关系。6例接受磁共振成像检查的患者被诊断为一氧化碳（CO）中毒后迟发性脑病。观察每位患者的临床表现。磁共振成像显示多处病变。大多数病变位于苍白球、皮质下白质和基底神经节。临床上表现为认知损伤、运动不能性缄默、大小便失禁、强哭、强笑以及舞蹈症和帕金森症等锥体外系综合征。几个月后，认知障碍有显著改善，而非自主运动仅略有改善。同时，脑部磁共振成像显示有明显改善。神经影像学表现与临床表现直接相关。
