Mira M, Stewart P M, Abraham S F
Department of Obstetrics and Gynaecology, University of Sydney, Croydon, Australia.
Am J Clin Nutr. 1989 Nov;50(5):940-4. doi: 10.1093/ajcn/50.5.940.
We studied biochemical measures of vitamin B-6, zinc, and copper in a group of 96 women and vitamin A and vitamin E concentrations in 89 women, all suffering from an eating disorder. Twenty-three control subjects were studied. Eating-disorder patients not taking vitamin or mineral supplements had significantly higher plasma concentrations of vitamins A and E than did control subjects (also not taking supplements). No difference was found in indices indicating vitamin B-6 status or in plasma zinc or copper concentrations. Self-induced vomiting was the only significant predictor of upper-quartile vitamin A concentrations. Upper-quartile vitamin B-6 activations (indicating lower vitamin B-6 activity) were significantly predicted only by low actual body weight. These results suggest that supplementation of micronutrient intake needs only to be considered for those eating-disorder patients at low weight and then only with water-soluble vitamins.
我们研究了96名患有饮食失调症女性的维生素B-6、锌和铜的生化指标,以及89名女性的维生素A和维生素E浓度。同时研究了23名对照受试者。未服用维生素或矿物质补充剂的饮食失调症患者,其血浆维生素A和E浓度显著高于对照受试者(对照受试者也未服用补充剂)。在表明维生素B-6状态的指标或血浆锌或铜浓度方面未发现差异。自我催吐是维生素A浓度处于上四分位数的唯一显著预测因素。维生素B-6活性处于上四分位数(表明维生素B-6活性较低)仅由实际体重过低显著预测。这些结果表明,仅需考虑为体重过低的饮食失调症患者补充微量营养素,且仅补充水溶性维生素。