脊髓多灶性硬脊膜内髓外毛细胞型星形细胞瘤：一例报告并文献复习
Multifocal Intradural Extramedullary Pilocytic Astrocytomas of the Spinal Cord: A Case Report and Review of the Literature.
作者信息
Basheer Azam, Rammo Richard, Kalkanis Steven, Felicella Michelle M, Chedid Mokbel
机构信息
Departments of Neurosurgery, Henry Ford Hospital, Detroit, Michigan, USA.
Departments of Pathology, Henry Ford Hospital, Detroit, Michigan, USA.
出版信息
Neurosurgery. 2017 Feb 1;80(2):E178-E184. doi: 10.1093/neuros/nyw029.
BACKGROUND AND IMPORTANCE
Pilocytic astrocytoma (PA) is among the most common of the central nervous system gliomas in the pediatric population; however, it is uncommon in adults. PAs of the spinal cord in adults are even rarer, with only a few cases found in the literature. We report here the first case in the literature of multifocal intradural extramedullary spinal cord PAs in an adult.
CLINICAL PRESENTATION
Our patient is a 56-yr-old female who presented with loss of balance and an ataxic gait. Multiple extramedullary spinal cord tumors were identified intraoperatively, the lesions completely resected, and all diagnosed as PAs.
CONCLUSION
This case illustrates a unique instance of multifocal intradural extramedullary spinal cord PAs in an adult with no previous history of PA during childhood, no known familial syndromes, and no brain involvement.
背景与重要性
毛细胞型星形细胞瘤（PA）是儿童中枢神经系统最常见的胶质瘤之一；然而，在成人中并不常见。成人脊髓PA更为罕见，文献中仅有少数病例报道。我们在此报告首例成人多灶性硬膜内髓外脊髓PA的病例。
临床表现
我们的患者是一名56岁女性，表现为平衡失调和共济失调步态。术中发现多个髓外脊髓肿瘤，病变被完全切除，所有肿瘤均诊断为PA。
结论
该病例显示了一例独特的成人多灶性硬膜内髓外脊髓PA，患者儿童期无PA病史，无已知家族综合征，且无脑部受累情况。
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