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一项基于人群的关于重症监护病房相关结局的观察性研究。重点关注出院后结局。

A population-based observational study of intensive care unit-related outcomes. With emphasis on post-hospital outcomes.

作者信息

Garland Allan, Olafson Kendiss, Ramsey Clare D, Yogendran Marina, Fransoo Randall

机构信息

1 Department of Internal Medicine.

出版信息

Ann Am Thorac Soc. 2015 Feb;12(2):202-8. doi: 10.1513/AnnalsATS.201405-201CME.

Abstract

RATIONALE

Many studies of critical illness outcomes have been restricted to short-term outcomes, selected diagnoses, and patients in one or a few intensive care units (ICUs).

OBJECTIVES

Evaluate a range of relevant outcomes in a population-based cohort of patients admitted to ICUs.

METHODS

Among all adult residents of the Canadian province of Manitoba admitted to ICUs over a 9-year period, we assessed ICU, hospital, 30-day, and 180-day mortality rates; ICU and hospital lengths-of-stay; Post-hospital use of hospital care, ICU care, outpatient physician care, medications, and home care; and Post-hospital residence location. We explored data stratified by age, sex, and separate categories of geocoded income for urban and rural residents. For Post-hospital use variables we compared ICU patients with those admitted to hospitals without the need for ICU care.

MEASUREMENTS AND MAIN RESULTS

After ICU admission there was a high initial death rate, which declined between 30 and 180 days and thereafter remained at the lower value. Hospital mortality was 19.0%, with 21.7% dying within 6 months of ICU admission. Women had higher hospital mortality than men (20.8 vs. 17.8%; P = 0.0008). Among urban residents there was a steady gradient of declining hospital mortality with rising income (P < 0.0001). Mean ICU length of stay was 3.96 days, increasing 0.11 d/yr over the study period (P = 0.001); median ICU length of stay was 2.33 days and did not change over time. In the year after ICU care, 41% were rehospitalized, 10% were readmitted to an ICU, 98% had outpatient physician visits, 96% used prescription medications, and 27% used home care services. Although most of these parameters were statistically higher than for hospitalizations not requiring ICU care, differences were generally small. Among hospital survivors, 2.7% were discharged to chronic care facilities, with 2.5% living in such facilities 3 months later.

CONCLUSIONS

Post-hospital medical resource use among ICU survivors is substantial, although similar to that after non-ICU hospitalization. Although the fraction of survivors unable to live independently was small, a larger fraction required home care services. Identifying Post-hospital supports needed by ICU survivors can be useful for policy makers and others responsible for healthcare planning.

摘要

原理

许多关于危重症结局的研究都局限于短期结局、特定诊断以及在一个或少数几个重症监护病房(ICU)的患者。

目的

评估以人群为基础的入住ICU患者队列中的一系列相关结局。

方法

在加拿大曼尼托巴省9年期间入住ICU的所有成年居民中,我们评估了ICU死亡率、医院死亡率、30天和180天死亡率;ICU住院时间和医院住院时间;出院后医院护理、ICU护理、门诊医生护理、药物和家庭护理的使用情况;以及出院后的居住地点。我们按年龄、性别以及城市和农村居民地理编码收入的不同类别对数据进行分层分析。对于出院后使用变量,我们将ICU患者与无需入住ICU的住院患者进行了比较。

测量指标和主要结果

入住ICU后初始死亡率较高,在30天至180天之间下降,此后保持在较低水平。医院死亡率为19.0%,21.7%的患者在入住ICU后6个月内死亡。女性的医院死亡率高于男性(20.8%对17.8%;P = 0.0008)。在城市居民中,随着收入增加,医院死亡率呈稳步下降趋势(P < 0.0001)。ICU平均住院时间为3.96天,在研究期间每年增加0.11天(P = 0.001);ICU住院时间中位数为2.33天,且随时间未发生变化。在接受ICU护理后的一年中,41%的患者再次住院,10%的患者再次入住ICU,98%的患者有门诊医生就诊,96%的患者使用处方药,27%的患者使用家庭护理服务。尽管这些参数大多在统计学上高于无需ICU护理的住院患者,但差异通常较小。在医院幸存者中,2.7%的患者出院后入住长期护理机构,3个月后有2.5%的患者仍居住在这类机构中。

结论

ICU幸存者出院后对医疗资源的使用量大,尽管与非ICU住院后的情况相似。虽然无法独立生活的幸存者比例较小,但需要家庭护理服务的比例较大。确定ICU幸存者出院后所需的支持对政策制定者和其他负责医疗保健规划的人员可能有用。

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