Gonzalez Sequeros O, Guijarro de Pablos J E, Moral Rubio J R, Ramirez Gonzalez J A
Anat Histol Embryol. 1989 Sep;18(3):205-26. doi: 10.1111/j.1439-0264.1989.tb00598.x.
A study of the crista ampullaris of the vestibular apparatus was carried out in chicken embryos. The study group included embryos between stages 24 and 39 of Hamburger-Hamilton. This study elucidates the relationship of the cupula with respect to the epithelium of the crista ampullaris. With electron microscopic examination, the rough endoplasmic reticulum of the crista epithelial sustentacular cells at developmental stage of 31 H-H, demonstrated dilatations containing secretory material. Vesicles, with adhering ribosomes appear to be formed from these dilatations. At later stages of development, the vesicular material took on the characteristics of the fibrillary material composing the cupula. In some cells, secretory vesicles are seen near the apical border of these cells, where they apparently secrete vesicular contents into the endolymphatic space, contributing to the formation of the cupula.
对鸡胚前庭器官的壶腹嵴进行了一项研究。研究组包括汉密尔顿-汉堡分期第24至39阶段的胚胎。本研究阐明了壶腹帽与壶腹嵴上皮的关系。通过电子显微镜检查，在汉密尔顿-汉堡分期第31阶段的发育阶段，壶腹嵴上皮支持细胞的粗面内质网显示出含有分泌物质的扩张。带有附着核糖体的囊泡似乎由这些扩张形成。在发育后期，囊泡物质呈现出构成壶腹帽的纤维状物质的特征。在一些细胞中，可见分泌囊泡靠近这些细胞的顶端边界，在那里它们显然将囊泡内容物分泌到内淋巴间隙，有助于壶腹帽的形成。
