Duan Lixia, Liu Jing, Chen Xi, Xiao Pengcheng, Zhao Yong
College of Science, North China University of Technology, Beijing, 100144 China.
Department of Mathematics, University of Evansville, Evansville, IN 47722 USA.
Cogn Neurodyn. 2017 Feb;11(1):91-97. doi: 10.1007/s11571-016-9411-3. Epub 2016 Sep 12.
Activity of neurons in the pre-Bötzinger complex within the mammalian brain stem has an important role in the generation of respiratory rhythms. Previous experimental results have shown that the dynamics of sodium and calcium within each cell may be responsible for various bursting mechanisms. In this paper, we study the bursting dynamics of the two-coupled pre-Bötzinger complex neurons. Using a combination of fast-slow decomposition and two-parameter bifurcation analysis, we explore the possible forms of dynamics that the model network can produce as well the transitions of in-phase and anti-phase bursting respectively.
哺乳动物脑干中前包钦格复合体神经元的活动在呼吸节律的产生中起着重要作用。先前的实验结果表明,每个细胞内钠和钙的动态变化可能是各种爆发机制的原因。在本文中,我们研究了两个耦合的前包钦格复合体神经元的爆发动力学。通过结合快慢分解和双参数分岔分析,我们探索了模型网络可能产生的动力学形式以及同相和反相爆发的转变。