一名患有特纳综合征的女性单次服用胺碘酮后出现QT间期延长和心脏骤停。
Prolonged QT interval and cardiac arrest after a single dose of amiodarone in a woman with Turner's syndrome.
作者信息
Nielsen Dorte Guldbrand, Nielsen Jens Cosedis, Trolle Christian, Gravholt Claus Højbjerg, Andersen Niels Holmark
机构信息
Department of Cardiology Aarhus University Hospital Aarhus N DK-8200 Denmark.
Department of Endocrinology and Internal Medicine Aarhus University Hospital Aarhus C DK-8000 Denmark.
出版信息
Clin Case Rep. 2017 Jan 21;5(2):154-158. doi: 10.1002/ccr3.802. eCollection 2017 Feb.
Low-dose QT-prolonging drugs may have detrimental effects on women with Turner's syndrome. Preventive measures would be to use potential QT-prolonging drugs with precaution and ensure that both before and during treatment, ECGs are evaluated and drug treatment stopped if the QT interval increases.
低剂量的可延长QT间期的药物可能会对患有特纳综合征的女性产生有害影响。预防措施是谨慎使用可能延长QT间期的药物，并确保在治疗前和治疗期间均对心电图进行评估，若QT间期延长则停止药物治疗。
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