Home Sweet Home: a Foxl1 Mesenchymal Niche for Intestinal Stem Cells.
作者信息
Mah Amanda T, Kuo Calvin J
机构信息
Department of Medicine, Hematology Division, Stanford University, Stanford, California.
出版信息
Cell Mol Gastroenterol Hepatol. 2016 Jan 25;2(2):116-117. doi: 10.1016/j.jcmgh.2016.01.004. eCollection 2016 Mar.
Abstract
摘要
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本文引用的文献
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Foxl1-expressing mesenchymal cells constitute the intestinal stem cell niche.表达Foxl1的间充质细胞构成肠道干细胞微环境。
Cell Mol Gastroenterol Hepatol. 2016 Feb 1;2(2):175-188. doi: 10.1016/j.jcmgh.2015.12.004.
2
Targeting PTPRK-RSPO3 colon tumours promotes differentiation and loss of stem-cell function.靶向 PTPRK-RSPO3 结肠肿瘤可促进分化并丧失干细胞功能。
Nature. 2016 Jan 7;529(7584):97-100. doi: 10.1038/nature16466. Epub 2015 Dec 23.
3
Stroma provides an intestinal stem cell niche in the absence of epithelial Wnts.基质在没有上皮 Wnt 的情况下为肠道干细胞提供了一个龛位。
Development. 2014 Jun;141(11):2206-15. doi: 10.1242/dev.104976.
4
Wnt secretion from epithelial cells and subepithelial myofibroblasts is not required in the mouse intestinal stem cell niche in vivo.在体内，上皮细胞和上皮下肌纤维母细胞的 Wnt 分泌对于小鼠肠道干细胞龛并不必需。
Stem Cell Reports. 2014 Jan 30;2(2):127-34. doi: 10.1016/j.stemcr.2013.12.012. eCollection 2014 Feb 11.
5
Intestinal stem cells and their defining niche.肠干细胞及其定义的龛位。
Curr Top Dev Biol. 2014;107:77-107. doi: 10.1016/B978-0-12-416022-4.00003-2.
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The intestinal crypt, a prototype stem cell compartment.肠隐窝，一个典型的干细胞隔室。
Cell. 2013 Jul 18;154(2):274-84. doi: 10.1016/j.cell.2013.07.004.
7
Notch in the intestine: regulation of homeostasis and pathogenesis.肠道中的 Notch：稳态调节与发病机制。
Annu Rev Physiol. 2013;75:263-88. doi: 10.1146/annurev-physiol-030212-183741. Epub 2012 Nov 26.
8
Functional intestinal stem cells after Paneth cell ablation induced by the loss of transcription factor Math1 (Atoh1).缺失转录因子 Math1（Atoh1）导致潘氏细胞消融后的功能性肠干细胞。
Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):8965-70. doi: 10.1073/pnas.1201652109. Epub 2012 May 14.
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Intact function of Lgr5 receptor-expressing intestinal stem cells in the absence of Paneth cells.Lgr5 受体表达肠干细胞在缺乏 Paneth 细胞的情况下的完整功能。
Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3932-7. doi: 10.1073/pnas.1113890109. Epub 2012 Feb 21.
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The intestinal stem cell markers Bmi1 and Lgr5 identify two functionally distinct populations.肠干细胞标志物 Bmi1 和 Lgr5 可识别出两个具有不同功能的群体。
Proc Natl Acad Sci U S A. 2012 Jan 10;109(2):466-71. doi: 10.1073/pnas.1118857109. Epub 2011 Dec 21.
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