Bayard Sophie, Moroni Christine, Gély-Nargeot Marie-Christine, Rossignol-Arifi Alexia, Kamara Emmanuelle, Raffard Stéphane
Laboratoire Epsylon, EA 4556 , Université Paul Valéry Montpellier 3, Montpellier, France.
Équipe "Neuropsychologie, Audition, Cognition, Action" (NACA), Laboratoire "Psychologie: Interactions, Temps, Emotions, Cognition" (PSITEC) EA 4072, Université Lille Nord de France, France.
Arch Clin Neuropsychol. 2017 Aug 1;32(5):592-597. doi: 10.1093/arclin/acx011.
We previously developed normative data for a French version of the Hayling Sentence Completion Test (f-HSCT) for adults and elderly people. The present study aimed to evaluate the clinical utility of the f-HSCT norms in two clinical populations in which inhibition dysfunction has been largely documented, i.e., Parkinson's disease (PD) and schizophrenia.
Eighty-five non-demented patients with idiopathic PD and 64 out-patients with schizophrenia completed the automatic and inhibition conditions of the f-HSCT. Time latencies and errors raw data of each patient were compared to the norms previously developed by the authors.
In the automatic condition, errors were rare in both clinical groups and time latencies on this condition felt within the normative data range. Compared with the standardized norms, 46% of patients with PD and 61% of patients with schizophrenia had a deviant performance (i.e., borderline or deficit) for the inhibition error score. The proportion of patients with a deviant performance on the inhibition response time score was similar in both clinical samples (respectively, 25% and 23%). Finally, slightly more than half of patients with PD and more than two-thirds of patients with schizophrenia had a deviant performance on at least one of the f-HSCT inhibition measures.
Our results suggest that the f-HSCT has a strong potential for characterizing inhibition of prepotent responses in PD and schizophrenia. Furthermore, it requires only a short administration time so it may be ideal to detect response inhibition in clinical populations with cognitive fatigue.
我们之前为法语版成人及老年人海林句子完成测验（f - HSCT）制定了常模数据。本研究旨在评估f - HSCT常模在两个已大量记录存在抑制功能障碍的临床群体中的临床效用，即帕金森病（PD）和精神分裂症。
85名非痴呆的特发性PD患者和64名精神分裂症门诊患者完成了f - HSCT的自动和抑制条件测试。将每位患者的时间潜伏期和错误原始数据与作者之前制定的常模进行比较。
在自动条件下，两个临床组的错误都很少，且该条件下的时间潜伏期在常模数据范围内。与标准化常模相比，46%的PD患者和61%的精神分裂症患者在抑制错误分数上表现异常（即临界或缺陷）。两个临床样本中抑制反应时间分数表现异常的患者比例相似（分别为25%和23%）。最后，略多于一半的PD患者和超过三分之二的精神分裂症患者在f - HSCT的至少一项抑制测量上表现异常。
我们的结果表明，f - HSCT在表征PD和精神分裂症中优势反应的抑制方面具有强大潜力。此外，它只需较短的测试时间，因此对于检测有认知疲劳临床群体中的反应抑制可能是理想的。
