Esparaz Anthony M, Ahmed Muneeb
Division of Vascular and Interventional Radiology, Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, WCC-308F, Rosenberg Building, 1 Deaconess Road, Boston, MA, 02215, USA.
Department of Radiology, Beth Israel Deaconess Medical Center, WCC 308-B, 1 Deaconess Road, Boston, MA, 02215, USA.
Cardiovasc Intervent Radiol. 2017 Jul;40(7):1118-1122. doi: 10.1007/s00270-017-1596-2. Epub 2017 Feb 7.
Local and systemic reactions to implanted metallic devices, particularly to those containing nickel, are well documented. Metal ions are released due to exposure of the metal to blood, proteins, other body fluids, and sheer mechanical stress. Metal ions then complex with native proteins and become antigens, which can elicit hypersensitivity reactions. Another case report depicts a specific allergic complication (early stent occlusion) related to metallic biliary stent implantation. We present a case of allergic symptoms, associated with eating, in a patient who developed nickel sensitivity after biliary metal stent placement confirmed by allergic skin testing to the same metallic biliary stent placed one year earlier. Symptoms resolved following partial removal of the non-epithelialized portion of the biliary stent.
植入金属装置，尤其是含镍装置后出现的局部和全身反应已有充分记录。由于金属暴露于血液、蛋白质、其他体液以及纯粹的机械应力，金属离子会被释放出来。然后金属离子与天然蛋白质结合形成抗原，进而引发过敏反应。另一例病例报告描述了与金属胆道支架植入相关的一种特定过敏并发症（早期支架闭塞）。我们报告了一例患者，在经皮肤过敏试验证实对一年前放置的同一金属胆道支架存在镍敏感性后，出现了与进食相关的过敏症状。在部分移除胆道支架未上皮化部分后，症状得到缓解。
