Tomita Kaoru
Heiwa Eye Clinic, 1-7-7 Ikebukuro, Toshima-ku, Tokyo, 170-0014, Japan.
Jpn J Ophthalmol. 2017 May;61(3):271-279. doi: 10.1007/s10384-017-0500-6. Epub 2017 Feb 7.
To analyze long-term visual development in children with Down syndrome who received early ophthalmological intervention.
A total of 125 children with Down syndrome who were examined before 6 years of age and followed up for more than 5 years were selected. Visual development, refraction, visual acuity testing, and the prescription of spectacles were examined retrospectively.
Mean visual acuity by age was as follows: 2 years, 1.13 ± 0.23 logarithm of the minimum angle of resolution (logMAR); 5 years, 0.55 ± 0.25 logMAR; 8 years, 0.27 ± 0.19 logMAR; 11 years, 0.17 ± 0.16 logMAR; and 14 years, 0.10 ± 0.15 logMAR. In 32 children (25.6%), visual acuity reached 0.0 logMAR or better. Hyperopia of +2D or more was observed in 132 eyes (52.8%), and astigmatism of 2D or more was observed in 153 eyes (61.2%). Subjective testing was difficult in many children prior to 4.5 years of age, and grating acuity testing was necessary. Spectacles were prescribed at a mean age of 3.5 ± 1.6 years in 120 children (96.0%). The average duration until the spectacles were worn constantly was 9.0 ± 9.3 months.
Early ophthalmological intervention and longitudinal care is important for children with Down syndrome.
分析接受早期眼科干预的唐氏综合征患儿的长期视力发育情况。
选取125例6岁前接受检查且随访时间超过5年的唐氏综合征患儿。回顾性分析其视力发育、屈光、视力测试及眼镜处方情况。
各年龄段的平均视力如下:2岁时,最小分辨角对数(logMAR)为1.13±0.23;5岁时,为0.55±0.25 logMAR;8岁时,为0.27±0.19 logMAR;11岁时,为0.17±0.16 logMAR;14岁时,为0.10±0.15 logMAR。32例患儿(25.6%)的视力达到或优于0.0 logMAR。132只眼(52.8%)存在2D或以上的远视,153只眼(61.2%)存在2D或以上的散光。许多4.5岁以下的患儿难以进行主观测试,因此需要进行光栅视力测试。120例患儿(96.0%)平均在3.5±1.6岁时开具了眼镜处方。眼镜持续佩戴的平均时长为9.0±9.3个月。
早期眼科干预和长期护理对唐氏综合征患儿很重要。