Richardson J D, Shina M A, Miller F B, Bergamini T M
Department of Surgery, University of Louisville, KY 40292.
Am Surg. 1989 Nov;55(11):675-80.
Percutaneous transluminal coronary angioplasty (PTCA) is being employed with increasing frequency for the treatment of coronary artery disease. PTCA involves the use of a larger sheath and catheter assembly than does cardiac catheterization, potentially increasing the risk of injury to the peripheral vessels used for access. Over an 18-month period, 295 angioplasty procedures resulted in six major vascular injuries (2%). The peripheral vascular complications that were recognized early included thrombosis of the common or superficial femoral artery in two patients and laceration of the iliac artery in two additional cases. Late complications included one superficial femoral artery aneurysm and one common iliac vein thrombosis. All patients required emergency operation at the time of recognition of their vascular complication, and five of six required multiple operative procedures. At operation, all but one patient had severe peripheral arterial disease. There was one death, three amputations, and multiple major complications. Although persistent dysrhythmias were common, major cardiac complications were unusual. These patients had prolonged hospital stays and high hospital costs. Although the incidence of arterial complications with PTCA is low, the consequences are potentially disastrous when they occur. Greater attention to basic evaluation for arterial disease is strongly recommended before elective PTCA, and informed consent about possible extremity complications is mandatory. These untoward results, with their prolonged stays and high costs, must be considered when evaluating the results of "nonoperative" treatment of coronary artery disease.
经皮腔内冠状动脉成形术(PTCA)在冠状动脉疾病治疗中的应用频率日益增加。与心脏导管插入术相比,PTCA使用的鞘管和导管组件更大,这可能会增加用于穿刺的外周血管受伤的风险。在18个月的时间里,295例血管成形术中有6例发生了严重血管损伤(2%)。早期发现的外周血管并发症包括2例股总动脉或股浅动脉血栓形成,另外2例髂动脉撕裂。晚期并发症包括1例股浅动脉动脉瘤和1例髂总静脉血栓形成。所有患者在发现血管并发症时均需紧急手术,6例中有5例需要多次手术。手术时,除1例患者外,所有患者均患有严重的外周动脉疾病。有1例死亡、3例截肢以及多种严重并发症。尽管持续性心律失常很常见,但严重心脏并发症并不多见。这些患者住院时间延长,住院费用高昂。虽然PTCA的动脉并发症发生率较低,但一旦发生,后果可能是灾难性的。强烈建议在择期PTCA前更加重视对动脉疾病的基础评估,并且必须就可能出现的肢体并发症获得知情同意。在评估冠状动脉疾病“非手术”治疗的结果时,必须考虑这些不良后果及其带来的延长住院时间和高昂费用。