Kain K C, Kelly M T
Division of Medical Microbiology, University of British Columbia, University Hospital, Vancouver, Canada.
Antimicrob Agents Chemother. 1989 Sep;33(9):1609-10. doi: 10.1128/AAC.33.9.1609.
Antimicrobial susceptibility testing was performed on 72 fecal isolates of Plesiomonas shigelloides from patients with diarrhea by using a standard agar dilution technique. All isolates were obtained from a single geographic location. Based on the in vitro activities demonstrated in this study, norfloxacin, ciprofloxacin, and trimethoprim may be effective as oral agents in the treatment of P. shigelloides diarrheal disease. For the parenteral treatment of extraintestinal infection, netilmicin and the cephalosporins had the best in vitro activity.
采用标准琼脂稀释技术,对72株从腹泻患者粪便中分离出的类志贺邻单胞菌进行了药敏试验。所有分离株均来自单一地理位置。根据本研究显示的体外活性,诺氟沙星、环丙沙星和甲氧苄啶可能作为口服药物有效治疗类志贺邻单胞菌腹泻病。对于肠外感染的肠外治疗,奈替米星和头孢菌素具有最佳的体外活性。