Kain K C, Kelly M T
Division of Medical Microbiology, University of British Columbia, Vancouver, Canada.
J Clin Microbiol. 1989 May;27(5):998-1001. doi: 10.1128/jcm.27.5.998-1001.1989.
Recent studies have suggested that Plesiomonas shigelloides is a cause of diarrhea. The present study addresses the clinical features, epidemiology, and response to antimicrobial therapy of P. shigelloides diarrhea. Thirty cases of P. shigelloides infection were defined by isolation of the organism from stool specimens, and 30 age-matched control patients were identified by detection of other enteric pathogens. Clinical and epidemiological information was obtained by interviewing the referring physicians and the patients. Of the P. shigelloides-infected patients, 71% had a history of recent tropical travel, but 29% acquired their infections locally in association with the consumption of seafood or untreated water or both. Seventy-eight percent of the P. shigelloides-infected patients had findings suggestive of colitis, and P. shigelloides-infected patients had a history of tropical travel, acute illness, abdominal pain, and prolonged symptoms significantly more often than did the control patients. Antimicrobial therapy significantly reduced the duration of illness in patients with Plesiomonas diarrhea. These results suggest that P. shigelloides is a significant cause of both locally acquired and traveler's diarrhea that may respond to antimicrobial therapy.
近期研究表明，类志贺邻单胞菌是腹泻的病因之一。本研究探讨了类志贺邻单胞菌腹泻的临床特征、流行病学及对抗菌治疗的反应。通过从粪便标本中分离出该病原体确诊30例类志贺邻单胞菌感染病例，并通过检测其他肠道病原体确定30例年龄匹配的对照患者。通过采访转诊医生和患者获取临床和流行病学信息。在类志贺邻单胞菌感染患者中，71%有近期热带旅行史，但29%是在当地因食用海鲜或未处理的水或两者兼而有之而感染。78%的类志贺邻单胞菌感染患者有提示结肠炎的表现，且类志贺邻单胞菌感染患者有热带旅行史、急性疾病、腹痛和症状持续时间延长的情况明显比对照患者更常见。抗菌治疗显著缩短了类志贺邻单胞菌腹泻患者的病程。这些结果表明，类志贺邻单胞菌是本地获得性腹泻和旅行者腹泻的重要病因，对抗菌治疗可能有反应。
