我们体内微生物的多样分子。

Microbial Molecules from the Multitudes within Us.

机构信息

Departments of Chemistry, Biochemistry, Microbiology and Genomics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

出版信息

Cell Metab. 2017 Feb 7;25(2):230-232. doi: 10.1016/j.cmet.2017.01.013.

DOI:10.1016/j.cmet.2017.01.013

PMID:28178564

Abstract

Chemists demonstrate in Cell that intestinal microbes are capable of synthesizing metabolites that look like clinical drugs and inhibit human targets. These results provide molecular resolution to the field of mammalian-microbial mutualism and highlight the potential for natural product discovery from the multitudes within us.

摘要

化学家在《细胞》杂志上证明，肠道微生物能够合成看起来像临床药物的代谢物，并抑制人体靶标。这些结果为哺乳动物-微生物共生领域提供了分子分辨率，并强调了从我们体内的众多微生物中发现天然产物的潜力。