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被遗忘的疾病——勒米尔综合征。

The forgotten disease - Lemierres syndrome.

作者信息

Farhan Ahmed, Shah Yawar Ali, Ali Bushra Tariq, Mumtaz Uzma, Farooq Umar

机构信息

Pakistan Institute of Medical Sciences, Islamabad.

出版信息

J Pak Med Assoc. 2016 Dec;66(12):1652-1655.

PMID:28179705
Abstract

Lemierre's syndrome refers to septic thrombosis of deep veins of the neck, is a rare and often life threatening complication following upper respiratory tract infections. We present here a case of Lemierre's syndrome in a previously healthy 30 years old female who had a febrile illness for two weeks with associated dysphagia, hoarse voice and right sided neck swelling. She was investigated for retropharyngeal and parapharyngeal abscess, granulomatosis with polyangiitis, tuberculosis and thyroiditis but finally concluded as Lemierre's syndrome based on the findings of thrombosis of the deep neck veins following respiratory tract infection, septic pulmonary emboli and clinical recovery with antibiotics and supportive care. Lemierres syndrome can be fatal if diagnosis and treatment is delayed. Strong clinical suspicion leads to early diagnosis and may prevent life threatening organ dysfunction.

摘要

勒米尔综合征是指颈部深静脉的脓毒性血栓形成,是上呼吸道感染后一种罕见且常危及生命的并发症。我们在此报告一例勒米尔综合征病例,患者为一名30岁既往健康的女性,发热两周,伴有吞咽困难、声音嘶哑和右侧颈部肿胀。她接受了咽后和咽旁脓肿、肉芽肿性多血管炎、结核病和甲状腺炎的检查,但最终根据呼吸道感染后颈部深静脉血栓形成、脓毒性肺栓塞以及抗生素和支持治疗后的临床恢复情况诊断为勒米尔综合征。如果诊断和治疗延迟,勒米尔综合征可能是致命的。强烈的临床怀疑可导致早期诊断,并可能预防危及生命的器官功能障碍。

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引用本文的文献

1
Lemierre's syndrome in a child.一名儿童患勒米尔综合征。
Pak J Med Sci. 2022 Jan;38(2):433-435. doi: 10.12669/pjms.38.ICON-2022.5773.
2
An Unusual Case of Modified Lemierre's Syndrome Caused by Staphylococcus aureus Cellulitis.一例由金黄色葡萄球菌蜂窝织炎引起的变异型勒米尔综合征罕见病例。
Am J Case Rep. 2020 Feb 2;21:e916575. doi: 10.12659/AJCR.916575.
3
Lemierre's syndrome: Case report and brief literature review.勒米尔综合征:病例报告及文献简要综述。
IDCases. 2017 Jul 27;10:15-17. doi: 10.1016/j.idcr.2017.07.009. eCollection 2017.