Zhao Andrew, Samannodi Mohammed, Tahir Muhammad, Bensman Sarah, Hocko Michael
Mayo Clinic Health System - Franciscan Healthcare, 815 10th Street, South La Crosse, WI, 54601, United States.
Department of medicine, Catholic Health System, University at Buffalo.
IDCases. 2017 Jul 27;10:15-17. doi: 10.1016/j.idcr.2017.07.009. eCollection 2017.
Lemierre's syndrome has been shown to be increasing in incidence in the past 20 years with one popular suggesting that said rise occurred from less aggressive antibacterial coverage. We report a case of Lemierre's syndrome and also reviewed the 15 most recent case reports. A previously healthy 25 year old male who initially developed sore throat and flu-like symptoms, was prescribed antibacterials as an outpatient but was hospitalized for worsening symptoms. He was later diagnosed with Lemierre's syndrome and improved clinically with IV antimicrobials alone. From our concise literature review, we determined that a decrease in antibiotic prescriptions may not fully explain why the incidence of Lemierre's has been increasing. Thus, future research should be focused in evaluating possible worsening susceptibilities to antibiotics and improvements on detection. We also advise physicians to be aware of the signs and symptoms of this rare but potentially fatal condition as well as the available detection methods and treatment.
在过去20年里，勒米尔综合征的发病率呈上升趋势，一种普遍观点认为，这种上升是由于抗菌覆盖不充分所致。我们报告了一例勒米尔综合征病例，并回顾了最近的15例病例报告。一名25岁的既往健康男性最初出现咽痛和流感样症状，门诊给予抗菌药物治疗，但因症状恶化而住院。他后来被诊断为勒米尔综合征，仅通过静脉使用抗菌药物临床症状就有所改善。通过我们简洁的文献综述，我们确定抗生素处方的减少可能无法完全解释勒米尔综合征发病率上升的原因。因此，未来的研究应集中于评估对抗生素敏感性可能的恶化情况以及检测方法的改进。我们还建议医生了解这种罕见但可能致命疾病的体征和症状以及现有的检测方法和治疗方法。
