Zashikhin A L
Arkh Anat Gistol Embriol. 1989 Jul;97(7):80-5.
At various stages of pre- and postnatal ontogenesis ultrastructure of contacts of smooth myocytes and nervous terminals in the white mice bronchial wall has been investigated. Nervous fibers grow into the forming tissue of the lung beginning from the 11th day of embryogenesis. By the end of the prenatal development the nervous fibers fasciculi with varicosites and having vesicles are localized at the distance of 100-300 nm from the developing myocytes. Formation of dense neuromuscular junctions with the distance of 35-60 nm between the axonal membranes and the myocyte is observed on the 10-15 day after birth. In mature animals combination of various types of neuromuscular connections is revealed; they ensure local and distant neurotrophic regulation. In the bronchial smooth musculature afferent connections are revealed, as well as connections of myocytic processes with the effectors. Terminals of the cholinergic type predominate, adrenergic effectors occur very seldom. There are terminals, in which combination of vesicles having various structure and diameter are observed.
在产前和产后个体发育的各个阶段，对白鼠支气管壁中平滑肌细胞与神经末梢接触的超微结构进行了研究。从胚胎发育的第11天开始，神经纤维长入肺的形成组织。到产前发育结束时，带有膨体和囊泡的神经纤维束位于距发育中的肌细胞100 - 300纳米处。出生后10 - 15天，观察到轴突膜与肌细胞之间距离为35 - 60纳米的致密神经肌肉接头的形成。在成熟动物中，揭示了各种类型神经肌肉连接的组合；它们确保局部和远距离的神经营养调节。在支气管平滑肌组织中，发现了传入连接以及肌细胞过程与效应器的连接。胆碱能型末梢占主导，肾上腺素能效应器很少出现。存在这样的末梢，其中观察到具有不同结构和直径的囊泡的组合。
