Kanai Akifumi, Matsumoto Shigehiro, Hayashi Norihito, Shimao Junko, Nagahara Yuki
Department of Research and Development Center for New Medical Frontiers, Kitasato University School of Medicine, Sagamihara, Japan.
Anesthesiology, Kitasato University School of Medicine, Sagamihara, Japan.
J Clin Anesth. 2017 Feb;36:90-93. doi: 10.1016/j.jclinane.2016.10.027. Epub 2016 Nov 30.
To examine the impact of visual stimulation (exciting red and tranquilizing green) on the score of the Numerical Rating Scale (NRS) questionnaire in patients with chronic pain.
Prospective randomized study.
Outpatient pain clinic of a university hospital.
Two hundred outpatients with chronic pain.
Patients were randomly assigned to receive the NRS questionnaire printed on either red paper (red group) or green paper (green group).
The questionnaire included 5 questions consisting of the NRS in the worst, in the least, and in the average pain during last week and the NRS at rest and on movement at present. Calculation of the sample size was based on power of 0.8 and α=.01.
The NRS scores were not different between the 2 groups. In patients on antidepressants (n=76) and with depression (n=49), the NRS scores, except the NRS in the worst pain during last week score in patients on antidepressants, were significantly higher in the red group than in the green group (all P≤.040). In the red group, the NRS scores were significantly higher in patients with than without depression (all P≤.003), whereas there was no difference in the scores between patients of the green group with and without depression.
Our findings suggest that visual/emotional stimuli and treatment with antidepressants alter the NRS score in patients with chronic pain.
探讨视觉刺激（刺激的红色和舒缓的绿色）对慢性疼痛患者数字评定量表（NRS）问卷评分的影响。
前瞻性随机研究。
大学医院门诊疼痛诊所。
200名慢性疼痛门诊患者。
患者被随机分配接受印在红色纸张上（红色组）或绿色纸张上（绿色组）的NRS问卷。
问卷包括5个问题，由上周最严重、最轻和平均疼痛程度的NRS以及目前静息和活动时的NRS组成。样本量的计算基于检验效能为0.8和α = 0.01。
两组之间的NRS评分无差异。在服用抗抑郁药的患者（n = 76）和患有抑郁症的患者（n = 49）中，除服用抗抑郁药患者上周最严重疼痛程度的NRS评分外，红色组的NRS评分显著高于绿色组（所有P≤0.040）。在红色组中，有抑郁症的患者的NRS评分显著高于无抑郁症的患者（所有P≤0.003），而绿色组中有抑郁症和无抑郁症的患者之间评分无差异。
我们的研究结果表明，视觉/情感刺激和抗抑郁药治疗会改变慢性疼痛患者的NRS评分。
