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对因急性静脉桥闭塞继发的ST段抬高型心肌梗死进行原发性经皮冠状动脉介入治疗天然慢性完全闭塞病变。

Primary percutaneous coronary intervention of native chronic total occlusions to treat ST elevation myocardial infarction secondary to acute vein graft occlusion.

作者信息

Deharo Pierre, Strange Julian W, Mozid Abdul

机构信息

Bristol Royal Infirmary, Bristol Heart Institute, Bristol, BS2 8HW, United Kingdom.

出版信息

Catheter Cardiovasc Interv. 2017 Aug 1;90(2):251-256. doi: 10.1002/ccd.26905. Epub 2017 Feb 10.

DOI:10.1002/ccd.26905
PMID:28185396
Abstract

Primary percutaneous coronary intervention (PCI) is the treatment modality of choice in patients presenting with ST elevation myocardial infarction (STEMI). Clinical outcomes have dramatically improved with the wide adoption of primary PCI in patients with STEMI because of acute thrombotic native coronary artery occlusion. However, patients with prior coronary artery bypass graft (CABG) surgery who present with STEMI because of acute saphenous vein graft (SVG) occlusion continue to have worse outcomes because of poor acute and long-term results of SVG stenting. Therefore, it may be preferable to treat the native coronary artery supplied by the occluded graft although this can be challenging if the native vessel is a chronic total occlusion (CTO). Recent advances in technology and techniques in CTO PCI have significantly improved the success rate and efficiency of CTO procedures. At our institution we have developed a high volume CTO programme with high success rates. We present three cases of acute inferior STEMI because of SVG occlusion which were treated with successful retrograde PCI of the native vessel CTO, utilising the occluded graft as a retrograde channel in two cases and native septal collaterals in the other. Thrombolysis In Myocardial Infarction (TIMI) 3 flow in the native coronary artery was achieved in all three cases with good acute outcomes. Our case series highlights the benefits of a high volume CTO programme. With recent advances in CTO techniques, acute PCI to native vessel CTO is feasible and may be the treatment of choice in selected cases of acute SVG failure. © 2017 Wiley Periodicals, Inc.

摘要

直接经皮冠状动脉介入治疗(PCI)是ST段抬高型心肌梗死(STEMI)患者的首选治疗方式。由于急性血栓形成导致自身冠状动脉闭塞,随着直接PCI在STEMI患者中的广泛应用,临床结局有了显著改善。然而,因急性大隐静脉桥血管(SVG)闭塞而发生STEMI的既往冠状动脉旁路移植术(CABG)患者,由于SVG支架置入的急性和长期效果不佳,其结局仍然较差。因此,治疗由闭塞桥血管供血的自身冠状动脉可能更可取,尽管如果自身血管是慢性完全闭塞(CTO),这可能具有挑战性。CTO PCI技术的最新进展显著提高了CTO手术的成功率和效率。在我们机构,我们已经开展了一个高容量的CTO项目,成功率很高。我们报告了3例因SVG闭塞导致的急性下壁STEMI病例,其中2例利用闭塞的桥血管作为逆行通道,另1例利用自身间隔侧支循环,成功对自身血管CTO进行了逆行PCI治疗。所有3例患者自身冠状动脉均实现了心肌梗死溶栓(TIMI)3级血流,急性结局良好。我们的病例系列突出了高容量CTO项目的益处。随着CTO技术的最新进展,对自身血管CTO进行急性PCI是可行的,并且可能是某些急性SVG失败病例的首选治疗方法。© 2017威利期刊公司

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