Akcay Murat
Department of Cardiology, Faculty of Medicine, Ondokuz Mayıs University, Samsun, Turkey.
J Tehran Heart Cent. 2020 Apr;15(2):69-72. doi: 10.18502/jthc.v15i2.4186.
Saphenous vein grafts (SVGs) are widely used conduits for the surgical revascularization of coronary arteries, but they are associated with poor long-term patency rates. Acute SVG thromboses often present as acute coronary syndrome and have an extensive atherosclerotic and thrombotic burden. Percutaneous coronary intervention (PCI) is the first treatment option; however, it carries a high risk of distal embolization, no-reflow, and periprocedural myocardial infarction. Reducing the thrombus burden and preventing distal embolization during PCI can be achieved by using some pharmacological strategies (e.g., glycoprotein IIb/IIIa antagonists) and devices (e.g., thrombectomy and filter devices). There are yet no better therapeutic options for patients undergoing PCI of SVG occlusions. Here, we introduce a 52-year-old male patient admitted with a typical acute chest pain of 1 hour's duration. Electrocardiography showed signs of acute inferoposterior myocardial infarction. A thrombotic SVG occlusion was detected in primary PCI, and a huge thrombus content was aspirated. After the thrombus aspiration with stent implantation, the chest pain was relieved and the ST-segment elevation was improved. The patient has been followed without any symptoms for 10 months.
大隐静脉移植物(SVG)是冠状动脉外科血管重建术中广泛使用的血管 conduit,但它们的长期通畅率较差。急性 SVG 血栓形成常表现为急性冠状动脉综合征,且有广泛的动脉粥样硬化和血栓形成负担。经皮冠状动脉介入治疗(PCI)是首选治疗方案;然而,它存在远端栓塞、无复流和围手术期心肌梗死的高风险。在 PCI 期间,通过使用一些药物策略(如糖蛋白 IIb/IIIa 拮抗剂)和器械(如血栓切除术和滤器装置)可以减轻血栓负担并预防远端栓塞。对于 SVG 闭塞接受 PCI 的患者,目前尚无更好的治疗选择。在此,我们介绍一名 52 岁男性患者,因持续 1 小时的典型急性胸痛入院。心电图显示急性下后壁心肌梗死迹象。在首次 PCI 中检测到血栓性 SVG 闭塞,并吸出大量血栓成分。在血栓抽吸并植入支架后,胸痛缓解,ST 段抬高改善。该患者已随访 10 个月,无任何症状。