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经皮抽吸血栓切除术成功治疗巨大血栓性大隐静脉移植血管闭塞:一例报告

Successful Treatment of a Huge Thrombotic Saphenous Vein Graft Occlusion with Aspiration Thrombectomy: A Case Report.

作者信息

Akcay Murat

机构信息

Department of Cardiology, Faculty of Medicine, Ondokuz Mayıs University, Samsun, Turkey.

出版信息

J Tehran Heart Cent. 2020 Apr;15(2):69-72. doi: 10.18502/jthc.v15i2.4186.

DOI:10.18502/jthc.v15i2.4186
PMID:33552197
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7825471/
Abstract

Saphenous vein grafts (SVGs) are widely used conduits for the surgical revascularization of coronary arteries, but they are associated with poor long-term patency rates. Acute SVG thromboses often present as acute coronary syndrome and have an extensive atherosclerotic and thrombotic burden. Percutaneous coronary intervention (PCI) is the first treatment option; however, it carries a high risk of distal embolization, no-reflow, and periprocedural myocardial infarction. Reducing the thrombus burden and preventing distal embolization during PCI can be achieved by using some pharmacological strategies (e.g., glycoprotein IIb/IIIa antagonists) and devices (e.g., thrombectomy and filter devices). There are yet no better therapeutic options for patients undergoing PCI of SVG occlusions. Here, we introduce a 52-year-old male patient admitted with a typical acute chest pain of 1 hour's duration. Electrocardiography showed signs of acute inferoposterior myocardial infarction. A thrombotic SVG occlusion was detected in primary PCI, and a huge thrombus content was aspirated. After the thrombus aspiration with stent implantation, the chest pain was relieved and the ST-segment elevation was improved. The patient has been followed without any symptoms for 10 months.

摘要

大隐静脉移植物(SVG)是冠状动脉外科血管重建术中广泛使用的血管 conduit,但它们的长期通畅率较差。急性 SVG 血栓形成常表现为急性冠状动脉综合征,且有广泛的动脉粥样硬化和血栓形成负担。经皮冠状动脉介入治疗(PCI)是首选治疗方案;然而,它存在远端栓塞、无复流和围手术期心肌梗死的高风险。在 PCI 期间,通过使用一些药物策略(如糖蛋白 IIb/IIIa 拮抗剂)和器械(如血栓切除术和滤器装置)可以减轻血栓负担并预防远端栓塞。对于 SVG 闭塞接受 PCI 的患者,目前尚无更好的治疗选择。在此,我们介绍一名 52 岁男性患者,因持续 1 小时的典型急性胸痛入院。心电图显示急性下后壁心肌梗死迹象。在首次 PCI 中检测到血栓性 SVG 闭塞,并吸出大量血栓成分。在血栓抽吸并植入支架后,胸痛缓解,ST 段抬高改善。该患者已随访 10 个月,无任何症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d78c/7825471/40caafcf10bc/JTHC-15-69-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d78c/7825471/0a37e86f36e6/JTHC-15-69-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d78c/7825471/40caafcf10bc/JTHC-15-69-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d78c/7825471/0a37e86f36e6/JTHC-15-69-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d78c/7825471/40caafcf10bc/JTHC-15-69-g002.jpg

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本文引用的文献

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Apixaban for the treatment of saphenous vein graft thrombosis presenting as unstable angina: a case report.阿哌沙班治疗表现为不稳定型心绞痛的隐静脉移植血管血栓形成:一例病例报告。
Thromb J. 2017 Apr 4;15:10. doi: 10.1186/s12959-017-0133-5. eCollection 2017.
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Primary percutaneous coronary intervention of native chronic total occlusions to treat ST elevation myocardial infarction secondary to acute vein graft occlusion.对因急性静脉桥闭塞继发的ST段抬高型心肌梗死进行原发性经皮冠状动脉介入治疗天然慢性完全闭塞病变。
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Use of Microvena Snare Catheter in Non-ST Elevation Myocardial Infarction Due to Saphenous Vein Graft Occlusive Thrombi.微静脉圈套导管在隐静脉桥闭塞性血栓导致的非ST段抬高型心肌梗死中的应用
Heart Views. 2012 Jan;13(1):19-21. doi: 10.4103/1995-705X.96665.
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Saphenous vein graft intervention.隐静脉移植介入治疗。
JACC Cardiovasc Interv. 2011 Aug;4(8):831-43. doi: 10.1016/j.jcin.2011.05.014.
8
Successful treatment of saphenous venous graft thrombus by tirofiban infusion.替罗非班输注成功治疗隐静脉移植物血栓。
Heart Lung. 2010 May-Jun;39(3):237-9. doi: 10.1016/j.hrtlng.2009.07.001.
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Acute anterior myocardial infarction due to aortosaphenous vein graft occlusion with very large thrombus burden.因大隐静脉移植血管闭塞且血栓负荷极大导致的急性前壁心肌梗死
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Combined use of aspiration catheter and distal embolisation protection device to facilitate angioplasty of a totally occluded saphenous vein graft.
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