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对65岁以上患者无移位股骨颈骨折治疗方法的系统评价,重点关注愈合率和缺血性坏死。

A systematic review of undisplaced femoral neck fracture treatments for patients over 65 years of age, with a focus on union rates and avascular necrosis.

作者信息

Xu Dan-Feng, Bi Fang-Gang, Ma Chi-Yuan, Wen Zheng-Fa, Cai Xun-Zi

机构信息

Department of Orthopaedic Surgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Jie-fang Road 88, Hangzhou, 310009, People's Republic of China.

Department of Orthopaedic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450001, People's Republic of China.

出版信息

J Orthop Surg Res. 2017 Feb 10;12(1):28. doi: 10.1186/s13018-017-0528-9.

Abstract

BACKGROUND

It remains unclear whether conservative treatment should be used to treat the common undisplaced femoral neck fractures that develop in the elderly. Herein, we systematically review the rates of union and avascular necrosis after conservative and surgical treatment of undisplaced femoral neck fractures.

METHODS

We searched the EMBASE, PubMed, OVID, Cochrane Library, Web of Science, and Scopus databases for randomized controlled trials or observational studies that assessed the outcomes of conservative or surgical treatments of undisplaced femoral neck fractures. No language or publication year limitation was imposed. Statistical analyses were performed with the aid of the chi-squared test. We evaluated the quality of each publication and the risk of bias.

RESULTS

Twenty-nine studies involving 5071 patients were ultimately included; 1120 patients were treated conservatively and 3951 surgically. The union rates were 68.8% (642/933) and 92.6% (635/686) in the former and latter groups, respectively (p < 0.001). The avascular necrosis rate in the conservatively treated group was 10.3% (39/380), while it was 7.7% (159/2074) in the surgically treated group (p = 0.09).

CONCLUSIONS

Surgery to treat undisplaced femoral neck fractures was associated with a higher union rate and a tendency toward less avascular necrosis than conservative treatment.

摘要

背景

对于老年患者中常见的无移位股骨颈骨折是否应采用保守治疗仍不明确。在此,我们系统回顾了无移位股骨颈骨折保守治疗和手术治疗后的愈合率及缺血性坏死率。

方法

我们检索了EMBASE、PubMed、OVID、Cochrane图书馆、科学网和Scopus数据库,以查找评估无移位股骨颈骨折保守治疗或手术治疗结果的随机对照试验或观察性研究。未设定语言或出版年份限制。借助卡方检验进行统计分析。我们评估了每项出版物的质量和偏倚风险。

结果

最终纳入了29项研究,涉及5071例患者;其中1120例接受保守治疗,3951例接受手术治疗。前一组和后一组的愈合率分别为68.8%(642/933)和92.6%(635/686)(p<0.001)。保守治疗组的缺血性坏死率为10.3%(39/380),而手术治疗组为7.7%(159/2074)(p=0.09)。

结论

与保守治疗相比,手术治疗无移位股骨颈骨折的愈合率更高,且缺血性坏死倾向更低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4867/5301374/833d003b6081/13018_2017_528_Fig1_HTML.jpg

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