Karogiannis N, Senior R
Department of Cardiovascular Medicine, Northwick Park Hospital, Harrow, UK.
Department of Echocardiography, Royal Brompton Hospital, Sydney Street, SW3 6NP, London, UK.
Herz. 2017 May;42(3):287-294. doi: 10.1007/s00059-017-4536-7.
Myocardial contrast echocardiography (MCE) is a well-established imaging technique in the assessment of patients with known or suspected coronary artery disease. The use of ultrasound contrast agents has optimized the evaluation of left ventricular function and, moreover, permits simultaneous assessment of the myocardial perfusion. This technique utilizes microbubbles that remain in the intravascular space and the contrast intensity reflects the concentration of the microbubbles in the myocardium. A homogeneous opacification of the myocardium after destruction of the microbubbles during high-power imaging is regarded as normal perfusion and absence of CAD. If the replenishment rate is reduced, this is suggestive of significant CAD. In comparison with other techniques, MCE shows comparable sensitivity, specificity, and diagnostic accuracy while it is an easy-to-perform bedside technique that can be a valuable tool for the clinician.
心肌对比超声心动图（MCE）是一种成熟的成像技术，用于评估已知或疑似冠状动脉疾病的患者。超声造影剂的使用优化了左心室功能的评估，此外，还能同时评估心肌灌注。该技术利用留在血管内空间的微泡，造影强度反映心肌中微泡的浓度。在高功率成像过程中微泡破坏后心肌均匀显影被视为正常灌注且无CAD。如果再充盈率降低，则提示存在严重CAD。与其他技术相比，MCE具有相当的敏感性、特异性和诊断准确性，同时它是一种易于操作的床旁技术，对临床医生来说可能是一种有价值的工具。
