Shinkai Koichi, Taira Yoshihisa, Kawashima Satoki, Suzuki Shiro, Suzuki Masaya
Department of Operative Dentistry, The Nippon Dental University School of Life Dentistry at Niigata.
Dent Mater J. 2017 May 31;36(3):348-356. doi: 10.4012/dmj.2016-148. Epub 2017 Feb 11.
The aim of this study was to histologically evaluate direct pulp capping using different all-in-one adhesives in rat teeth. Five all-in-one adhesives and a control material (MTA) were used. Each material was applied on the exposed pulp, and each cavity was subsequently restored with the resin composite. Rats were sacrificed 14 days after the surgical procedure. Serial stained sections were histologically evaluated for examining pulp tissue disorganization (PTD), inflammatory cell infiltration (ICI), dentin bridge formation (DBF), and bacterial penetration (BP). We found that rat pulps, which were direct capped with all-in-one adhesives, showed various degrees of PTD, ICI, and DBF depending on the material, and that there were no complete dentin bridges. In contrast, rat pulps capped with MTA showed no PTD and ICI, and there were complete dentin bridges in all, but one specimen. No BP was observed in any specimen.
本研究的目的是从组织学角度评估在大鼠牙齿中使用不同的一体化粘合剂进行直接盖髓术的效果。使用了五种一体化粘合剂和一种对照材料（MTA）。将每种材料应用于暴露的牙髓，随后用树脂复合材料修复每个窝洞。在手术操作14天后处死大鼠。对连续染色切片进行组织学评估，以检查牙髓组织紊乱（PTD）、炎症细胞浸润（ICI）、牙本质桥形成（DBF）和细菌侵入（BP）情况。我们发现，用一体化粘合剂直接盖髓的大鼠牙髓，根据材料不同，表现出不同程度的PTD、ICI和DBF，且没有完整的牙本质桥。相比之下，用MTA盖髓的大鼠牙髓未出现PTD和ICI，除一个标本外，其余所有标本均有完整的牙本质桥。在任何标本中均未观察到BP。
