Bojanic Nebojsa, Bumbasirevic Uros, Bojanic Gordana, Vukovic Ivan, Milojevic Bogomir, Pekmezovic Tatjana
Clinic of Urology, Clinical Center of Serbia, Belgrade, Serbia.
Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
J Surg Oncol. 2017 Mar;115(3):287-290. doi: 10.1002/jso.24502. Epub 2017 Feb 13.
To evaluate the results of testis-sparing surgery (TSS) in patients, with small testicular lesions and a normal contralateral testicle.
In all, 28 patients were treated with TSS for small testicular lesions and a normal contralateral testicle. TSS was considered in patients with testicular lesions smaller than 2 cm and no evidence of metastatic disease.
The mean age of patients was 35.3 ± 7.3 years, while the mean diameter of the testicular lesions was 11.4 ± 3.7 mm. After pathological examination, 18 patients (64.3%) were diagnosed with stromal tumors and miscellaneous lesions, while 10 (35.7%) had a germ cell tumor. The median follow-up time for the former group was 33 months and no recurrences were observed. In one patient with germ cell tumor, immediate orchiectomy was performed, while the remaining nine were followed-up (median time, 45 months). One patient developed local recurrence after 39 months.
Excellent outcomes for benign lesions could be achieved using TSS. TSS could be offered safely in highly selected patients with germ cell tumors, specifically within a clinical trial but there is more data needed regarding the potential risks and benefits. J. Surg. Oncol. 2017;115:287-290. © 2016 Wiley Periodicals, Inc.
评估保留睾丸手术（TSS）治疗睾丸小病灶且对侧睾丸正常患者的效果。
共有28例睾丸小病灶且对侧睾丸正常的患者接受了TSS治疗。睾丸病灶小于2 cm且无转移疾病证据的患者被纳入TSS治疗。
患者的平均年龄为35.3±7.3岁，睾丸病灶的平均直径为11.4±3.7 mm。病理检查后，18例患者（64.3%）被诊断为间质肿瘤和其他病变，10例（35.7%）患有生殖细胞肿瘤。前一组的中位随访时间为33个月，未观察到复发。1例生殖细胞肿瘤患者立即进行了睾丸切除术，其余9例进行了随访（中位时间45个月）。1例患者在39个月后出现局部复发。
使用TSS可获得良性病变的良好治疗效果。对于高度选择的生殖细胞肿瘤患者，尤其是在临床试验中，可安全地提供TSS，但关于潜在风险和益处还需要更多数据。《外科肿瘤学杂志》2017年；115:287 - 290。©2016威利期刊公司。
