Woo Lynn L, Ross Jonathan H
Department of Pediatric Urology, Rainbow Babies & Children's Hospital, Cleveland, OH, USA.
Department of Urology, Rush University Medical Center, Chicago, IL, USA.
Transl Androl Urol. 2020 Oct;9(5):2400-2407. doi: 10.21037/tau-19-815.
While radical orchiectomy remains the gold standard for testicular cancer, partial orchiectomy has become a well-accepted organ-sparing approach for benign testicular tumors in pre-pubertal patients. The aims of testicular-sparing surgery include prevention of over-treatment, preservation of future hormonal and reproductive function, and provision of a durable cure. For pre-pubertal patients, who have a high likelihood of benign lesions, partial orchiectomy provides effective treatment, owing to the high reliability of scrotal ultrasound (US) and intraoperative frozen section. In adolescent and young adult patients, who are more likely to harbor malignant pathology, the role of partial orchiectomy is less clear. Testis-sparing surgery is being reported with greater frequency in the adult literature for small testicular masses and for situations in which radical orchiectomy would result in an anorchia. More recently, a testis-sparing approach has also been described for carefully-selected post-pubertal pediatric patients. This review will highlight the role of partial orchiectomy in pediatric patients (<18 years old).
虽然根治性睾丸切除术仍是睾丸癌的金标准,但对于青春期前患者的良性睾丸肿瘤,部分睾丸切除术已成为一种广泛接受的保留器官的方法。保留睾丸手术的目的包括防止过度治疗、保留未来的激素和生殖功能以及实现持久治愈。对于良性病变可能性高的青春期前患者,由于阴囊超声(US)和术中冰冻切片的高可靠性,部分睾丸切除术可提供有效的治疗。在更有可能患有恶性病变的青少年和年轻成年患者中,部分睾丸切除术的作用尚不清楚。在成人文献中,对于小的睾丸肿块以及根治性睾丸切除术会导致无睾症的情况,保留睾丸手术的报道越来越多。最近,对于精心挑选的青春期后儿科患者,也描述了一种保留睾丸的方法。本综述将重点介绍部分睾丸切除术在儿科患者(<18岁)中的作用。