Department of Reproductive Imaging, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.
Department of Radiology, Medical Imaging Center, Advanced Diagnostic and Interventional Radiology Research Center (ADIR), Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Arch Iran Med. 2017 Feb;20(2):101-104.
Assisted reproductive treatment (ART) cycle is an expensive procedure with low implantation and pregnancy rate; therefore, it is necessary to evaluate the predictors of success in these patients.
The relationship between endometrial echopattern and pregnancy rate was evaluated.
The endometrial echopattern was analyzed prospectively on the day of human chorionic gonadotropin (HCG) administration in 280 in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) cycles with 8-14 mm endometrial thickness at Royan institute in 2013-2014. Based on echopattern, three groups were developed: pattern A (Triple line), pattern B (Heterogeneous-echogen) and pattern C (Homogeneous-echogen). Pregnancy rate (PR) was compared between all groups. Data was analyzed using SPSS (v.18, Chicago, IL, USA), and descriptive tests such as Chi-square and analytical tests like logistic regression, for controlling confounder variables like age.
Among 280 patients finally evaluable, the distribution of endometrial echopattern on the day of HCG administration was 127 patients (45.4%) in group A, 98 patients (35%) in group B and 55 patients (19.6%) in group C. The highest PR per transfer pertained to group A (49.6%), and the lowest to group B (32.7%).
The presence of pattern A (Triple line) appears more likely to favor pregnancy. Therefore, ultrasonographic evaluation of endometrial echopattern on the day of HCG administration has prognostic value in clinical settings for predicting implantation in ART cycle.
辅助生殖治疗（ART）周期是一个昂贵的程序，其着床率和妊娠率都较低；因此，有必要评估这些患者成功的预测因素。
评估子宫内膜回声图与妊娠率之间的关系。
在 2013-2014 年，Royan 研究所对 280 个人类绒毛膜促性腺激素（HCG）给药日的体外受精/胞浆内精子注射（IVF/ICSI）周期中，进行了 8-14 毫米子宫内膜厚度的前瞻性子宫内膜回声图分析。根据回声图，将三组分为：A 型（三线）、B 型（异质-回声）和 C 型（同质-回声）。比较所有组之间的妊娠率（PR）。使用 SPSS（v.18，芝加哥，IL，美国）分析数据，采用卡方检验和逻辑回归等分析方法，控制年龄等混杂变量。
在 280 例最终可评估的患者中，HCG 给药日子宫内膜回声图的分布为 A 组 127 例（45.4%），B 组 98 例（35%），C 组 55 例（19.6%）。每移植周期的最高 PR 与 A 组（49.6%）相关，而 B 组最低（32.7%）。
存在 A 型（三线）模式似乎更有利于妊娠。因此，HCG 给药日的子宫内膜回声图超声评估在预测 ART 周期着床方面具有临床预测价值。
