Singh D R, Srivastava A K, Bhartiya D, Bajpai V K, Hasan M
Department of Anatomy, King George's Medical College, Lucknow, India.
Brain Res Bull. 1989 Sep;23(3):175-81. doi: 10.1016/0361-9230(89)90144-5.
The caudal part of the fourth ventricle in adult rhesus monkeys, of both sexes, revealed the area postrema (AP) to be composed of bilateral spindle-shaped elevations located ventromedial to the gracile tubercles. Supraependymal (SE) elements, comprised of SE cells and/or fibre processes could be seen near the medial margin of a narrow oligociliated strip separating the nonciliated AP from the profusely ciliated vagal triangle (VT). In general, these consisted of multilobed ganglion-like cell clusters interconnected by fasciculated fibre processes with varicosities along their lengths. Thinner processes radiating from the cell clusters and varicosities traversed towards the VT for short distances and often appeared to penetrate the underlying ependyma. The thicker fibre processes which exhibited a fasciculated configuration extended between raised nodule-like areas in the ventricular floor. The majority of such areas exhibited an uneven surface due to the presence of numerous membranous folds over them. Near the periphery of nodular areas as well as along the fasciculated fibre processes interconnecting them, a few bouton-like protrusions were discernible. The SE elements observed in the caudal portion of the fourth ventricular floor are suggestive of comprising some integrative pathways between the ventricular cerebrospinal fluid and subependymal functional centres in the vicinity of the AP, a circumventricular organ having diverse functions.
成年恒河猴两性第四脑室的尾部显示，最后区（AP）由位于薄束结节腹内侧的双侧纺锤形隆起组成。在将无纤毛的AP与纤毛丰富的迷走神经三角（VT）分开的狭窄少纤毛带的内侧边缘附近，可以看到由室管膜上（SE）细胞和/或纤维突起组成的SE成分。一般来说，这些成分由多叶状的神经节样细胞簇组成，这些细胞簇通过有束状纤维突起相互连接，纤维突起沿其长度有静脉曲张。从细胞簇和静脉曲张放射出的较细突起向VT短距离穿过，并且常常似乎穿透下面的室管膜。呈现束状结构的较粗纤维突起在心室底部的隆起结节状区域之间延伸。由于这些区域上存在许多膜状褶皱，大多数此类区域的表面不均匀。在结节状区域的周边以及连接它们的束状纤维突起沿线，可以看到一些纽扣状突起。在第四脑室底部尾部观察到的SE成分提示，在心室脑脊液与AP附近的室管膜下功能中心之间存在一些整合途径，AP是一个具有多种功能的室周器官。
