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CHEER慢性鼻-鼻窦炎诊疗模式全国性研究:疾病共病情况及与手术相关的因素

CHEER National Study of Chronic Rhinosinusitis Practice Patterns: Disease Comorbidities and Factors Associated with Surgery.

作者信息

Chapurin Nikita, Pynnonen Melissa A, Roberts Rhonda, Schulz Kristine, Shin Jennifer J, Witsell David L, Parham Kourosh, Langman Alan, Carpenter David, Vambutas Andrea, Nguyen-Huynh Anh, Wolfley Anne, Lee Walter T

机构信息

1 Division of Head and Neck Surgery and Communication Sciences, Duke University Medical Center, Durham, North Carolina, USA.

2 Department of Otolaryngology, University of Michigan, Ann Arbor, Michigan, USA.

出版信息

Otolaryngol Head Neck Surg. 2017 Apr;156(4):751-756. doi: 10.1177/0194599817691476. Epub 2017 Feb 14.

Abstract

Objectives (1) Describe national patterns of chronic rhinosinusitis (CRS) care across academic and community practices. (2) Determine the prevalence of comorbid disorders in CRS patients, including nasal polyposis, allergic rhinitis, asthma, and cystic fibrosis. (3) Identify demographic, clinical, and practice type factors associated with endoscopic sinus surgery (ESS). Study Design Multisite cross-sectional study. Setting Otolaryngology's national research network CHEER (Creating Healthcare Excellence through Education and Research). Subjects and Methods A total of 17,828 adult patients with CRS were identified, of which 10,434 were seen at community practices (59%, n = 8 sites) and 7394 at academic practices (41%, n = 10 sites). Multivariate logistic regression was used to evaluate the association between demographic, practice type, and clinical factors and the odds of a patient undergoing ESS. Results The average age was 50.4 years; 59.5% of patients were female; and 88.3% were Caucasian. The prevalence of comorbid diseases was as follows: allergic rhinitis (35.1%), nasal polyposis (13.3%), asthma (4.4%), and cystic fibrosis (0.2%). In addition, 24.8% of patients at academic centers underwent ESS, as compared with 12.3% at community sites. In multivariate analyses, nasal polyposis (odds ratio [OR], 4.28), cystic fibrosis (OR, 2.42), and academic site type (OR, 1.86) were associated with ESS ( P < .001), while adjusting for other factors. Conclusions We describe practice patterns of CRS care, as well as demographic and clinical factors associated with ESS. This is the first study of practice patterns in CRS utilizing the CHEER network and may be used to guide future research.

摘要

目标

(1)描述学术机构和社区医疗机构中慢性鼻-鼻窦炎(CRS)的全国性诊疗模式。(2)确定CRS患者中合并症的患病率,包括鼻息肉、变应性鼻炎、哮喘和囊性纤维化。(3)确定与鼻内镜鼻窦手术(ESS)相关的人口统计学、临床和医疗机构类型因素。研究设计:多中心横断面研究。研究地点:耳鼻喉科的全国性研究网络CHEER(通过教育和研究创造卓越医疗)。研究对象和方法:共识别出17828例成年CRS患者,其中10434例在社区医疗机构就诊(占59%,共8个地点),7394例在学术机构就诊(占41%,共10个地点)。采用多因素logistic回归分析评估人口统计学、医疗机构类型和临床因素与患者接受ESS的几率之间的关联。结果:平均年龄为50.4岁;59.5%的患者为女性;88.3%为白种人。合并症的患病率如下:变应性鼻炎(35.1%)、鼻息肉(13.3%)、哮喘(4.4%)和囊性纤维化(0.2%)。此外,学术中心24.8%的患者接受了ESS,而社区医疗机构为12.3%。在多因素分析中,调整其他因素后,鼻息肉(比值比[OR]为4.28)、囊性纤维化(OR为2.42)和学术机构类型(OR为1.86)与ESS相关(P < .001)。结论:我们描述了CRS的诊疗模式以及与ESS相关的人口统计学和临床因素。这是利用CHEER网络对CRS诊疗模式进行的首次研究,可用于指导未来的研究。

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