Berrettini W H, Cappellari C B, Nurnberger J I, Gershon E S
Neuropsychobiology. 1987;17(1-2):15-8. doi: 10.1159/000118334.
Beta-adrenergic receptor function has been the subject of much research in manic-depressive illness. Lymphoblast beta receptor binding was analyzed by Scatchard plot, using cell lines established from 17 unrelated bipolar subjects and 14 normals. No significant differences in affinity or density of beta receptors were found, in contrast to a previous report. Both the affinity and density of receptors appeared to be a stable characteristic of a cell line, as determined by repeated assay of the same cell lines.
β-肾上腺素能受体功能一直是躁郁症诸多研究的主题。利用从17名无亲缘关系的双相情感障碍患者和14名正常人建立的细胞系，通过Scatchard图分析了淋巴母细胞β受体结合情况。与之前的一份报告相反，未发现β受体在亲和力或密度上有显著差异。通过对同一细胞系的重复检测确定，受体的亲和力和密度似乎都是细胞系的一个稳定特征。
