Osterhage H R, Kottwitz J, Heckl W
Urologe A. 1987 Jul;26(4):229-34.
The recently developed absorbable materials demonstrate a constant and reproducible high quality when compared with the resorbable suture materials. However, based on in vitro studies by different authors the use of these materials in infected urine is not recommended. We investigated in vivo in infected urines the stability of the suture materials composed of polyglycolic acid, and compared the results obtained in vitro and in vivo. In a controlled study the stability of the absorbable suture materials polyglycolic acid, polyglactin 910 and polydioxanon 4/0 USP were tested in infected urine in vivo and in vitro. In 21 patients with infected urine the suture materials were placed into the bladder for 7 days. In another experiment these materials were incubated up to 7 days in culture flasks with infected urine. After that the suture materials were examined by densitometry and electrone microscopy. When using the results obtained in vitro in clinical work caution is recommended. However, the in vivo tests show that the stability of the newly developed absorbable materials is not influenced dramatically by the infected urine.
与可吸收缝线材料相比，最近开发的可吸收材料展现出恒定且可重复的高质量。然而，根据不同作者的体外研究，不建议在感染尿液中使用这些材料。我们在感染尿液中对由聚乙醇酸组成的缝线材料进行了体内研究，并比较了体外和体内获得的结果。在一项对照研究中，对可吸收缝线材料聚乙醇酸、聚乳酸-910和聚二氧杂环己酮4/0 USP在感染尿液中的体内和体外稳定性进行了测试。在21例感染尿液患者中，将缝线材料置于膀胱中7天。在另一项实验中，将这些材料在装有感染尿液的培养瓶中孵育长达7天。之后，通过密度测定法和电子显微镜对缝线材料进行检查。在临床工作中使用体外获得的结果时，建议谨慎。然而，体内测试表明，新开发的可吸收材料的稳定性不会受到感染尿液的显著影响。
