Trimbos J B, Niggebrugge A, Trimbos R, Van Rijssel E J
Department of Gynaecology, Leiden University Medical Center, The Netherlands.
Eur J Surg. 1995 May;161(5):319-22.
To study the mechanical knotting abilities of the new synthetic absorbable monofilament suture poliglecaprone 25 (Monocryl) compared with other absorbable suture materials.
Experimental laboratory study.
Knotted loops (3/0 USP) of five synthetic absorbable sutures: Monocryl (poliglecaprone 25), PDS-2 (polydioxanone), Maxon (polyglyconate), Vicryl (polyglactin-910) and Dexon-Plus (polyglycolic acid). Three different knots were tested in a total of 150 experiments.
Mean loop holding capacity (LHC) of 10 experiments, expressed in Newtons (N).
Monofilament Maxon tied significantly more secure knots than the other sutures. Sliding knots of Monocryl (poliglecaprone 25) were similar to, and three-throw square knots were less secure than those tied with monofilament PDS-2. Braided Dexon-Plus was superior to Monocryl for sliding knots but comparable for square knots. Braided Vicryl did not differ significantly from Monocryl.
The mechanical knot performance of Monocryl is identical to that of Vicryl, less than that of one other synthetic absorbable monofilament suture (Maxon) and comparable to or somewhat less than the other alternative (PDS-2). These findings, together with other characteristics such as degradation rate, should be used to define the application of Monocryl.
研究新型合成可吸收单丝缝线聚乙醇酸交酯25（爱惜康）与其他可吸收缝线材料相比的机械打结能力。
实验性实验室研究。
五种合成可吸收缝线的打结环（3/0美国药典规格）：爱惜康（聚乙醇酸交酯25）、PDS-2（聚二氧杂环己酮）、Maxon（聚甘醇酸酯）、薇乔（聚乙交酯-910）和 Dexon-Plus（聚乙醇酸）。在总共150次实验中测试了三种不同的结。
10次实验的平均环扣持力（LHC），以牛顿（N）表示。
单丝Maxon打的结比其他缝线明显更牢固。爱惜康（聚乙醇酸交酯25）的滑结与单丝PDS-2打的结相似，三叠方结不如单丝PDS-2打的结牢固。编织的Dexon-Plus在滑结方面优于爱惜康，但在方结方面相当。编织的薇乔与爱惜康没有显著差异。
爱惜康的机械打结性能与薇乔相同，低于另一种合成可吸收单丝缝线（Maxon），与另一种替代品（PDS-2）相当或略低。这些发现，连同降解率等其他特性，应用于确定爱惜康的应用。
