Sever'ianova L A
Zh Vyssh Nerv Deiat Im I P Pavlova. 1987 May-Jun;37(3):471-7.
DOCA (0.3 mg/kg i.p.) inhibited the shock-induced aggression in male rats. This behavioural reaction was also inhibited by activation of brain beta-adrenergic and nicotinic receptors. The inhibitory hormone effect was potentiated to a considerable extent (p less than 0.05-0.001) by central beta-adrenergic stimulation but was blocked by beta-antagonist administration. However, it was independent of facilitatory and inhibitory actions on the brain nicotinic receptors. It is concluded that the DOCA inhibitory effect on the shock-induced defensive fighting involved the facilitation of the brain beta-adrenergic receptor activation.
去氧皮质酮醋酸酯（0.3毫克/千克，腹腔注射）可抑制雄性大鼠因电击诱发的攻击行为。脑β-肾上腺素能受体和烟碱样受体的激活也能抑制这种行为反应。中枢β-肾上腺素能刺激可在很大程度上增强抑制性激素效应（p小于0.05 - 0.001），但β-拮抗剂给药可阻断该效应。然而，其与对脑烟碱样受体的促进和抑制作用无关。结论是，去氧皮质酮醋酸酯对电击诱发的防御性争斗的抑制作用涉及促进脑β-肾上腺素能受体的激活。
