Sever'ianova L A, Plotnikov D V
Fiziol Zh SSSR Im I M Sechenova. 1986 Dec;72(12):1614-8.
ACTH4-10 and ACTH5-10 enhanced the fear response and footshock-induced aggression in male rats (50 and 150 mcg/kg, i.p.). ACTH4-10 seemed to produce the corticotropin (ACTH1-39) neuromodulatory behavioral effect which involved the facilitation of the brain muscarinic receptor activation.
促肾上腺皮质激素4-10和促肾上腺皮质激素5-10增强了雄性大鼠(腹腔注射,剂量为50和150微克/千克)的恐惧反应和电击诱发的攻击行为。促肾上腺皮质激素4-10似乎产生了促肾上腺皮质激素(促肾上腺皮质激素1-39)的神经调节行为效应,这涉及促进脑毒蕈碱受体的激活。