Menant Jasmine C, Migliaccio Americo A, Hicks Cameron, Lo Joanne, Meinrath Daniela, Ratanapongleka Mayna, Turner Jessica, Sturnieks Daina L, Delbaere Kim, Titov Nickolai, McVeigh Catherine, Close Jacqueline C T, Lord Stephen R
Neuroscience Research Australia, University of New South Wales, Sydney, Australia.
School of Public Health & Community Medicine, University of New South Wales, Sydney, Australia.
BMC Geriatr. 2017 Feb 15;17(1):56. doi: 10.1186/s12877-017-0450-3.
Dizziness is a frequently reported symptom in older people that can markedly impair quality of life. This manuscript presents the protocol for a randomised controlled trial, which has the main objective of determining the impact of comprehensive assessment followed by a tailored multifaceted intervention in reducing dizziness episodes and symptoms, improving associated impairments to balance and gait and enhancing quality of life in older people with self-reported significant dizziness.
Three hundred people aged 50 years or older, reporting significant dizziness in the past year will be recruited to participate in the trial. Participants allocated to the intervention group will receive a tailored, multifaceted intervention aimed at treating their dizziness symptoms over a 6 month trial period. Control participants will receive usual care. The primary outcome measures will be the frequency and duration of dizziness episodes, dizziness symptoms assessed with the Dizziness Handicap Inventory, choice-stepping reaction time and step time variability. Secondary outcomes will include health-related quality of life measures, depression and anxiety symptoms, concern about falling, balance and risk of falls assessed with the physiological fall risk assessment. Analyses will be by intention-to-treat.
The study will determine the effectiveness of comprehensive assessment, combined with a tailored, multifaceted intervention on dizziness episodes and symptoms, balance and gait control and quality of life in older people experiencing dizziness. Clinical implications will be evident for the older population for the diagnosis and treatment of dizziness.
The study is registered with the Australia New Zealand Clinical Trials Registry ACTRN12612000379819 .
头晕是老年人中经常报告的症状，会显著损害生活质量。本手稿介绍了一项随机对照试验的方案，其主要目的是确定在对自我报告有明显头晕症状的老年人中，进行综合评估并随后进行量身定制的多方面干预对减少头晕发作和症状、改善平衡和步态相关损伤以及提高生活质量的影响。
将招募300名年龄在50岁及以上、在过去一年中报告有明显头晕症状的人参与试验。分配到干预组的参与者将在为期6个月的试验期内接受旨在治疗其头晕症状的量身定制的多方面干预。对照组参与者将接受常规护理。主要结局指标将是头晕发作的频率和持续时间、用头晕残障量表评估的头晕症状、选择步反应时间和步时间变异性。次要结局将包括与健康相关的生活质量指标、抑郁和焦虑症状、对跌倒的担忧、用生理跌倒风险评估评估的平衡和跌倒风险。分析将采用意向性分析。
该研究将确定综合评估结合量身定制的多方面干预对头晕的老年人的头晕发作和症状、平衡和步态控制以及生活质量的有效性。对于老年人头晕的诊断和治疗，临床意义将是明显的。
该研究已在澳大利亚新西兰临床试验注册中心注册，注册号为ACTRN12612000379819。
