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四肢行走:帕金森病中北欧健走的系统评价

Walking on four limbs: A systematic review of Nordic Walking in Parkinson disease.

作者信息

Bombieri Federica, Schena Federico, Pellegrini Barbara, Barone Paolo, Tinazzi Michele, Erro Roberto

机构信息

Department of Neuroscience, Biomedicine and Movement Sciences, Università di Verona, Verona, Italy.

Department of Neuroscience, Biomedicine and Movement Sciences, Università di Verona, Verona, Italy; CeRiSM (Research Centre of Mountain Sport and Health), University of Verona, Rovereto, Italy.

出版信息

Parkinsonism Relat Disord. 2017 May;38:8-12. doi: 10.1016/j.parkreldis.2017.02.004. Epub 2017 Feb 6.

Abstract

Nordic Walking is a relatively high intensity activity that is becoming increasingly popular. It involves marching using poles adapted from cross-country skiing poles in order to activate upper body muscles that would not be used during normal walking. Several studies have been performed using this technique in Parkinson disease patients with contradictory results. Thus, we reviewed here all studies using this technique in Parkinson disease patients and further performed a meta-analysis of RCTs where Nordic Walking was evaluated against standard medical care or other types of physical exercise. Nine studies including four RCTs were reviewed for a total of 127 patients who were assigned to the Nordic Walking program. The majority of studies reported beneficial effects of Nordic Walking on either motor or non-motor variables, but many limitations were observed that hamper drawing definitive conclusions and it is largely unclear whether the benefits persist over time. It would appear that little baseline disability is the strongest predictor of response. The meta-analysis of the 4 RCTs yielded a statistically significant reduction of the UPDRS-3 score, but its value of less than 1 point does not appear to be clinically meaningful. Well-designed, large RCTs should be performed both against standard medical care and other types of physical exercise to definitively address whether Nordic Walking can be beneficial in PD.

摘要

北欧式健走是一项强度相对较高且越来越受欢迎的活动。它包括使用借鉴越野滑雪杖改良的杆子行进,以激活正常行走时不会用到的上身肌肉。已经对帕金森病患者开展了多项使用该技术的研究,但结果相互矛盾。因此,我们在此回顾了所有针对帕金森病患者使用该技术的研究,并进一步对将北欧式健走与标准医疗护理或其他类型体育锻炼进行对比评估的随机对照试验进行了荟萃分析。共回顾了9项研究,其中包括4项随机对照试验,涉及总共127名被分配到北欧式健走项目的患者。大多数研究报告了北欧式健走对运动或非运动变量的有益影响,但也观察到许多局限性,这妨碍得出明确结论,而且很大程度上不清楚这些益处是否能长期持续。似乎基线残疾程度低是反应的最强预测因素。对4项随机对照试验的荟萃分析得出统一帕金森病评定量表第三部分(UPDRS - 3)评分在统计学上有显著降低,但其降低幅度小于1分似乎并无临床意义。应该针对标准医疗护理和其他类型体育锻炼开展设计良好的大型随机对照试验,以明确解决北欧式健走对帕金森病是否有益的问题。

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