Auger Nathalie, Potter Brian J, Smargiassi Audrey, Bilodeau-Bertrand Marianne, Paris Clément, Kosatsky Tom
Centre de recherche du Centre hospitalier de l'Université de Montréal (Auger, Potter, Bilodeau-Bertrand); Institut national de santé publique du Québec (Auger, Smargiassi, Bilodeau-Bertrand, Paris); Division of Cardiology, Department of Medicine (Potter), Centre hospitalier de l'Université de Montréal; Department of Occupational and Environmental Health (Smargiassi), School of Public Health, Université de Montréal, Montréal, Que.; Faculty of Science (Paris), Aix-Marseille Université, Marseille, France; National Collaborating Centre for Environmental Health (Kosatsky), British Columbia Centre for Disease Control, Vancouver, BC
Centre de recherche du Centre hospitalier de l'Université de Montréal (Auger, Potter, Bilodeau-Bertrand); Institut national de santé publique du Québec (Auger, Smargiassi, Bilodeau-Bertrand, Paris); Division of Cardiology, Department of Medicine (Potter), Centre hospitalier de l'Université de Montréal; Department of Occupational and Environmental Health (Smargiassi), School of Public Health, Université de Montréal, Montréal, Que.; Faculty of Science (Paris), Aix-Marseille Université, Marseille, France; National Collaborating Centre for Environmental Health (Kosatsky), British Columbia Centre for Disease Control, Vancouver, BC.
CMAJ. 2017 Feb 13;189(6):E235-E242. doi: 10.1503/cmaj.161064.
Although aggregate data suggest a link between snowfall and myocardial infarction (MI), individual risk has yet to be assessed. We evaluated the association between quantity and duration of snowfall and the risk of MI using nonaggregated administrative health data.
We used a case-crossover study design to investigate the association between snowfall and hospital admission or death due to MI in the province of Quebec, Canada, between November and April during 1981-2014. The main exposure measures were quantity (in centimetres) and duration (in hours) of snowfall by calendar day. We computed odds ratios (ORs) and 95% confidence intervals (CIs) for the association between daily snowfall and MI, adjusted for minimum daily temperatures.
In all, 128 073 individual hospital admissions and 68 155 deaths due to MI were included in the analyses. The likelihood of MI was increased the day after a snowfall among men but not among women. Compared with 0 cm, 20 cm of snowfall was associated with an OR of 1.16 for hospital admission (95% CI 1.11-1.21) and 1.34 for death (95% CI 1.26-1.42) due to MI the following day among men. Corresponding ORs among women were 1.01 (95% CI 0.95-1.07) and 1.04 (95% CI 0.96-1.13). Similar but smaller associations were observed for snowfall duration (0 h v. 24 h) and MI.
Both the quantity and duration of snowfall were associated with subsequent risk of hospital admission or death due to MI, driven primarily by an effect in men. These data have implications for public health initiatives in regions with snowstorms.
尽管总体数据表明降雪与心肌梗死(MI)之间存在联系,但个体风险尚未得到评估。我们使用非汇总的行政健康数据评估了降雪量和降雪持续时间与MI风险之间的关联。
我们采用病例交叉研究设计,调查了1981年至2014年11月至4月期间加拿大魁北克省降雪与因MI住院或死亡之间的关联。主要暴露指标是按日历日计算的降雪量(以厘米为单位)和降雪持续时间(以小时为单位)。我们计算了每日降雪与MI之间关联的优势比(OR)和95%置信区间(CI),并对每日最低气温进行了调整。
分析共纳入了128073例因MI住院的个体和68155例因MI死亡的个体。降雪后第二天,男性发生MI的可能性增加,而女性则没有。与降雪量为0厘米相比,降雪量为20厘米时,男性第二天因MI住院的OR为1.16(95%CI 1.11 - 1.21),因MI死亡的OR为1.34(95%CI 1.26 - 1.42)。女性的相应OR分别为1.01(95%CI 0.95 - 1.07)和1.04(95%CI 0.96 - 1.13)。降雪持续时间(0小时与24小时)与MI之间也观察到了类似但较小的关联。
降雪量和降雪持续时间均与随后因MI住院或死亡的风险相关,主要是由男性中的效应驱动。这些数据对有暴风雪地区的公共卫生举措具有启示意义。