Oda Kazunori, Aso Shotaro, Hattori Yujiro, Yamaguchi Fumio, Matsui Hiroki, Fushimi Kiyohide, Yasunaga Hideo, Morita Akio
Department of Neurological Surgery, Nippon Medical School, Bunkyo-ku, Japan.
Department of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Japan.
Surg Neurol Int. 2021 Feb 23;12:69. doi: 10.25259/SNI_882_2020. eCollection 2021.
Chronic subdural hematoma (CSDH) is a frequently observed disease in neurosurgical practice. Although first snowfall has been considered to increase the onset of CSDH, few reports have assessed the relationship between snowfall and CSDH. In this study, we aimed to investigate the relationship between CSDH onset and first snowfall events.
This retrospective study was based on the Japanese Diagnosis Procedure Combination inpatient database from July 1, 2010, to March 31, 2016, and on the global observation of snowfall events in Japan obtained from the Japan Meteorological Agency. We used a binomial approximation to evaluate the average number of CSDH patients after first snowfall events compared with that before first snowfall events. We calculated the odds ratio of CSDH onset on the first snowfall.
We identified 8526 CSDH patients from the database. A total of 5573 (65.4%) were observed before first snowfall events, and 2953 (34.6%) after first snowfall events. The first snowfall of winter was significantly associated with a reduction in the occurrence of CSDH (odds ratio, 0.53; 95% confidence interval; 0.51-0.55). In subgroup analysis, only the first snowfall in October was not associated with reduction in the occurrence of CSDH.
First snowfall events did not affect the onset of CSDH in Japan.
慢性硬膜下血肿（CSDH）是神经外科实践中常见的疾病。尽管初雪被认为会增加CSDH的发病几率，但很少有报告评估降雪与CSDH之间的关系。在本研究中，我们旨在调查CSDH发病与初雪事件之间的关系。
这项回顾性研究基于2010年7月1日至2016年3月31日的日本诊断程序组合住院患者数据库，以及从日本气象厅获得的日本降雪事件全球观测数据。我们使用二项式近似法评估初雪事件后与初雪事件前CSDH患者的平均数量。我们计算了初雪时CSDH发病的比值比。
我们从数据库中识别出8526例CSDH患者。其中，5573例（65.4%）在初雪事件前被观察到，2953例（34.6%）在初雪事件后被观察到。冬季的初雪与CSDH发生率的降低显著相关（比值比，0.53；95%置信区间：0.51 - 0.55）。在亚组分析中，只有10月的初雪与CSDH发生率的降低无关。
在日本，初雪事件不会影响CSDH的发病。
