血浆置换治疗药物性胆汁淤积所致难治性瘙痒
Plasmapheresis for Refractory Pruritus due to Drug-Induced Cholestasis.
作者信息
Al-Azzawi Hasan, Patel Ruchi, Sood Gagan, Kapoor Sumit
机构信息
Department of Pulmonary, Critical Care and Sleep, Baylor College of Medicine, Houston, TX, USA.
Department of Abdominal Transplantation, Baylor College of Medicine, Houston, TX, USA.
出版信息
Case Rep Gastroenterol. 2017 Jan 6;10(3):814-818. doi: 10.1159/000454674. eCollection 2016 Sep-Dec.
Pruritus can be a distressing symptom seen in various cholestatic disorders. It is treated with medications like bile acid sequestrants. Drug-induced cholestasis usually resolves with withdrawal of the causative medication. We describe a case of refractory pruritus due to drug-induced cholestasis, not improved with withdrawal of the drug, managed effectively with multiple sessions of plasmapheresis.
瘙痒是各种胆汁淤积性疾病中出现的一种令人苦恼的症状。可使用胆汁酸螯合剂等药物进行治疗。药物性胆汁淤积通常在停用致病药物后缓解。我们描述了一例因药物性胆汁淤积导致的难治性瘙痒病例，停药后未改善，通过多次血浆置换有效治疗。
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