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胆固醇稳态概述。

An Overview of Cholesterol Homeostasis.

作者信息

Gelissen Ingrid C, Brown Andrew J

机构信息

Faculty of Pharmacy, The University of Sydney, Sydney, NSW, 2006, Australia.

School of Biotechnology and Biomolecular Sciences, The University of New South Wales, Sydney, NSW, 2052, Australia.

出版信息

Methods Mol Biol. 2017;1583:1-6. doi: 10.1007/978-1-4939-6875-6_1.

Abstract

Cholesterol has long been implicated in diverse aspects of human health and disease. As this lipid is both vital and lethal, ensuring that its levels are kept in check is important for maintaining health. However, studying cholesterol homeostasis can be challenging due to the extreme hydrophobic nature of cholesterol and the membranous world it inhabits. This volume of Methods in Molecular Biology brings together 21 techniques covering the gamut of cholesterol homeostasis.

摘要

长期以来,胆固醇一直与人类健康和疾病的各个方面存在关联。由于这种脂质既至关重要又具有致命性,因此确保其水平得到控制对于维持健康很重要。然而,由于胆固醇具有极强的疏水性以及它所处的膜环境,研究胆固醇稳态可能具有挑战性。本卷《分子生物学方法》汇集了21种涵盖胆固醇稳态各个方面的技术。

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