Stern Kenan W D, Gauvreau Kimberlee, Emani Sitaram, Geva Tal
Department of Cardiology, Boston Children's Hospital, Boston, Massachusetts, USA.
Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.
Congenit Heart Dis. 2017 May;12(3):350-356. doi: 10.1111/chd.12450. Epub 2017 Feb 16.
Stage 1 Norwood palliation is one of the highest risk procedures in congenital cardiac surgery. Patients with superior technical performance scores have more favorable outcomes. Intraoperative epicardial echocardiography may allow the surgeon to address residual lesions prior to leaving the operating room, resulting in improved technical performance. The ability of intraoperative epicardial echocardiography to visualize the relevant anatomy and its association with outcomes is not known.
A standardized intraoperative epicardial echocardiography protocol was developed and performed at the conclusion of Stage 1 Norwood palliation. Data pertaining to visualization of relevant anatomy, and comparison of intraoperative echocardiogram findings with other postoperative investigations was performed. Clinical outcomes, including technical performance, were collected. A historical cohort who received either no echocardiogram or a nonstandardized examination was used as a comparison group.
Thirty on-protocol and 30 preprotocol patients, 22 of whom had a nonstandardized intraoperative epicardial echocardiogram, were studied. Compared with preprotocol, visualization of the relevant anatomy was significantly increased for the Damus-Kaye-Stansel anastomosis (93% vs. 68% P = .03) and branch pulmonary arteries (70% vs. 36%, P = .02). One residual lesion requiring immediate operative reintervention was diagnosed in the preprotocol group. There were 5 patients in each cohort with residual lesions during the postoperative hospitalization that were not appreciated on the intraoperative echocardiogram. Technical performance, rates of reintervention and clinical outcomes were not significantly different between the two groups.
Intraoperative epicardial echocardiography is technically feasible and increases visualization of the relevant anatomy. Larger investigations may be warranted to determine if there is clinical benefit to such an approach.
一期诺伍德姑息手术是先天性心脏外科手术中风险最高的手术之一。技术表现评分较高的患者预后更佳。术中的心外膜超声心动图可使外科医生在离开手术室前处理残余病变,从而提高手术技术水平。术中的心外膜超声心动图可视化相关解剖结构的能力及其与预后的关系尚不清楚。
制定并在一期诺伍德姑息手术结束时实施标准化的心外膜超声心动图检查方案。收集与相关解剖结构可视化有关的数据,并将术中超声心动图检查结果与其他术后检查结果进行比较。收集包括手术技术水平在内的临床结果。将未接受超声心动图检查或接受非标准化检查的历史队列作为对照组。
研究了30例符合方案组患者和30例方案前患者,其中22例接受了非标准化的心外膜超声心动图检查。与方案前相比,达穆斯-凯-斯坦塞尔吻合术(93%对68%,P = 0.03)和分支肺动脉(70%对36%,P = 0.02)的相关解剖结构可视化显著增加。方案前组诊断出1例需要立即进行手术再次干预的残余病变。每个队列中有5例患者在术后住院期间存在残余病变,术中超声心动图未发现。两组之间的手术技术水平、再次干预率和临床结果无显著差异。
术中的心外膜超声心动图在技术上是可行的,可增加相关解剖结构的可视化。可能需要进行更大规模的研究来确定这种方法是否具有临床益处。