Luo S Q, Zhang Y X
First Military Medical University, PLA, Guangzhou.
Zhonghua Zhong Liu Za Zhi. 1987 Mar;9(2):115-7.
Ultrastructure of 15 brain tumors (6 astrocytomas, 5 meningiomas, 2 medulloblastomas and 2 Schwannomas) was observed by transmission electron microscope. In astrocytoma, both the fibrous and protoplasmic astrocytes were found. There were abundant capillaries among the tumor cells. The glia limitans outside the base membrane of certain capillaries were destroyed to different degrees. It indicates that the blood brain barrier may be damaged. Ultrastructurally, medulloblastoma cells may be divided into types I and II. The former was poorly differentiated but the latter was differentiated differently. Meningioma was similar to Schwannoma with complex cell membrane projections. The former had a lot of round mitochondria and filaments in the projections, between which desmosomes were observed. Schwannoma had the typical collagenous fibers among the projections. As to the epithelioid ultrastructure of meningioma, the authors speculate that the majority of meningiomas originate from the mesothelial cells of the arachnoid granulations.
用透射电子显微镜观察了15例脑肿瘤（6例星形细胞瘤、5例脑膜瘤、2例髓母细胞瘤和2例神经鞘瘤）的超微结构。在星形细胞瘤中，发现了纤维型和原浆型星形胶质细胞。肿瘤细胞间有丰富的毛细血管。某些毛细血管基膜外的胶质界膜有不同程度的破坏。这表明血脑屏障可能受损。在超微结构上，髓母细胞瘤细胞可分为I型和II型。前者分化差，而后者分化程度不同。脑膜瘤与神经鞘瘤相似，有复杂的细胞膜突起。前者在突起中有许多圆形线粒体和细丝，其间可见桥粒。神经鞘瘤在突起中有典型的胶原纤维。关于脑膜瘤的上皮样超微结构，作者推测大多数脑膜瘤起源于蛛网膜颗粒的间皮细胞。
