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奇美拉分枝杆菌与心脏手术。

Mycobacterium chimaera and cardiac surgery.

机构信息

Austin Health, Melbourne, VIC

Monash Health, Melbourne, VIC.

出版信息

Med J Aust. 2017 Feb 20;206(3):132-135. doi: 10.5694/mja16.00670.

Abstract

There is an ongoing investigation into infections with non-tuberculous mycobacteria associated with contaminated heater-cooler units used in cardiac surgery. The overall risk is low, but surgical site and disseminated infections have been reported, including one possible case in Australia, mainly with surgery involving implantation of prosthetic material. Mycobacterium chimaera infection should be considered in patients who have previously undergone surgery with cardiopulmonary bypass and who present with cardiac or disseminated infection or sternal wound infection unresponsive to standard antibiotic therapy. Where cases are suspected, patients should be investigated and managed in consultation with an infectious diseases physician and/or clinical microbiologist. If cases are confirmed or heater-cooler devices are found to be contaminated, details should be reported to the hospital infection control team, the jurisdictional health department, the Therapeutic Goods Administration and the Australian distributor of the affected heater-cooler unit(s). Measures to manage risk should include communicating with relevant hospital departments, ensuring that the manufacturer's updated instructions for use are followed, regular testing of machines, and reviewing the location of machines when in use.

摘要

正在调查与心脏手术中使用的受污染热交换器单元相关的非结核分枝杆菌感染。总体风险较低,但已报告手术部位和播散性感染,包括澳大利亚的一个可能病例,主要涉及涉及植入假体材料的手术。对于先前接受过心肺旁路手术且出现心脏或播散性感染或胸骨伤口感染且对标准抗生素治疗无反应的患者,应考虑感染分枝杆菌 chimaera。在怀疑有病例的情况下,应与传染病医生和/或临床微生物学家协商对患者进行调查和管理。如果确诊病例或发现热交换器装置受到污染,应向医院感染控制小组、管辖卫生部门、治疗商品管理局和受影响的热交换器单元的澳大利亚分销商报告详细信息。管理风险的措施应包括与相关医院部门沟通,确保遵循制造商更新的使用说明,定期对机器进行测试,并在使用时审查机器的位置。

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