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胎儿性别对因各种指征引产的初产妇分娩结局的影响。

The Effect of Fetal Gender on the Delivery Outcome in Primigravidae Women with Induced Labours for all Indications.

作者信息

Antonakou Angeliki, Papoutsis Dimitrios

机构信息

Assistant Professor, Department of Midwifery, Midwifery School, 'Alexander' Technological Educational Institute of Thessaloniki , Greece, Thessaloniki, Greece .

Post-Doctoral Research Fellow, Obstetrician and Gynaecologist, Department of Obstetrics and Gynaecology, Shrewsbury and Telford Hospitals NHS Trust , United Kingdom .

出版信息

J Clin Diagn Res. 2016 Dec;10(12):QC22-QC25. doi: 10.7860/JCDR/2016/22099.9104. Epub 2016 Dec 1.

DOI:10.7860/JCDR/2016/22099.9104
PMID:28208944
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5296517/
Abstract

INTRODUCTION

There is increasing evidence of a gender-related phenomenon where the presence of a male fetus may have an adverse effect on the outcome of pregnancy.

AIM

The aim of this study was to investigate the effect of fetal gender on the delivery outcome in primigravidae women with induced labours.

MATERIALS AND METHODS

This was an observational cohort study of primigravidae women who had Induction Of Labour (IOL) for all indications during a two-year period. Women with breech vaginal deliveries, stillbirths, multiple pregnancies and elective Caesarean Section (CS) were excluded.

RESULTS

Of the 936 eligible patients identified, 493(52.6%) gave birth to male neonates and 443(47.4%) to female neonates. Age, ethnicity, Body Mass Index (BMI) and smoking were similar between women that delivered male and female neonates. More than half of all women were induced for post-date pregnancies. In women who gave birth to male neonates, the CS delivery rate was higher than in those with female neonates (23.7% vs 17.8%; p=0.029). Though emergency admission rates to the neonatal Intensive Care Unit (ICU) and arterial/venous pH from umbilical cord sampling immediately after birth were similar between male and female neonates, nevertheless male neonates had lower Apgar scores of <7 at 1 minute after birth (p=0.02).

CONCLUSIONS

This study has shown that, male gender fetuses have a higher CS delivery rate in primigravidae women undergoing IOL and may be more vulnerable to fetal compromise when in labour.

摘要

引言

越来越多的证据表明存在一种与性别相关的现象,即男性胎儿的存在可能对妊娠结局产生不利影响。

目的

本研究的目的是调查胎儿性别对初产妇引产分娩结局的影响。

材料与方法

这是一项对初产妇进行的观察性队列研究,这些初产妇在两年期间因各种指征接受引产。排除臀位阴道分娩、死产、多胎妊娠和择期剖宫产的妇女。

结果

在确定的936名符合条件的患者中,493名(52.6%)分娩出男婴,443名(47.4%)分娩出女婴。分娩男婴和女婴的妇女在年龄、种族、体重指数(BMI)和吸烟情况方面相似。超过一半的妇女因过期妊娠而引产。分娩男婴的妇女剖宫产率高于分娩女婴的妇女(23.7%对17.8%;p=0.029)。虽然男婴和女婴出生后立即入住新生儿重症监护病房(ICU)的急诊率以及脐带血采样的动脉/静脉pH值相似,但男婴出生后1分钟时Apgar评分<7的比例较低(p=0.02)。

结论

本研究表明,在接受引产的初产妇中,男性胎儿的剖宫产率较高,并且在分娩时可能更容易出现胎儿窘迫。

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Effect of fetal gender on pregnancy outcomes in Northern China.中国北方胎儿性别对妊娠结局的影响。
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Foetal Gender and Obstetric Outcome.胎儿性别与产科结局
Geburtshilfe Frauenheilkd. 2016 Mar;76(3):255-260. doi: 10.1055/s-0041-109198.
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Combined effect of fetal sex and advanced maternal age on pregnancy outcomes.胎儿性别与高龄产妇对妊娠结局的综合影响。
Med Sci Monit. 2015 Apr 20;21:1124-30. doi: 10.12659/MSM.893057.
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Cross sectional study in China: fetal gender has adverse perinatal outcomes in mainland China.中国的横断面研究:胎儿性别对中国大陆围产期结局有不良影响。
BMC Pregnancy Childbirth. 2014 Oct 26;14:372. doi: 10.1186/s12884-014-0372-4.
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Integrative transcriptome meta-analysis reveals widespread sex-biased gene expression at the human fetal-maternal interface.整合转录组荟萃分析揭示了人类胎儿-母体界面广泛存在的性别偏向性基因表达。
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Weight gain regardless of pre-pregnancy BMI and influence of fetal gender in response to labor induction in postdate pregnancy.过期妊娠中,无论孕前体重指数如何,体重增加情况以及胎儿性别对引产反应的影响。
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Libyan J Med. 2013;8. doi: 10.3402/ljm.v8i0.20008. Epub 2013 Jan 8.
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