Baniasadi Shadi, Alaeen Zeinab, Behgam Shadmehr Mohammad
Tracheal Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Pharmaceutical Sciences Branch, Islamic Azad University, Tehran, Iran.
Tanaffos. 2016;15(3):154-159.
Surgical site infections (SSIs) are common complications following surgeries and increase mortality, morbidity and healthcare costs. The use of antimicrobial prophylaxis is an effective measure to prevent development of SSIs. This study aimed to evaluate the current use of prophylactic antibiotics in thoracic surgeries in Iran.
A descriptive study was conducted among thoracic surgeons in order to assess their knowledge, attitude and practice (KAP) about surgical antibiotic prophylaxis (SAP). A four-section multiple-choice questionnaire was designed and hand-delivered to registered thoracic surgeons. The surgeons' answers were considered correct when they were in accordance to the American Society of Health-System Pharmacist (ASHP) guidelines.
Seventy thoracic surgeons were requested to participate in this study and their response rate was 71.4%. Thirty-five (70%) surgeons had good knowledge about appropriate SAP. However, less than half of the respondents were aware of appropriate SAP in case of Ig E-mediated reaction to penicillin and risk of Gram-negative infections. The surgeon's attitude score about the need for local and national guidelines for SAP was 78% and 90%, respectively. Accordance of the physician's practice with ASHP guidelines regarding timing of the first dosage of SAP was acceptable while correct administration of an intraoperative dose was 40% in agreement with the guideline.
Although thoracic surgeons had a good attitude towards antibiotic prophylaxis guidelines, their knowledge and practice should be improved for proper administration of SAP.
手术部位感染（SSIs）是手术后常见的并发症，会增加死亡率、发病率和医疗成本。使用抗菌药物预防是预防手术部位感染发生的有效措施。本研究旨在评估伊朗胸外科手术中预防性抗生素的当前使用情况。
对胸外科医生进行了一项描述性研究，以评估他们对外科手术抗生素预防（SAP）的知识、态度和实践（KAP）。设计了一份包含四个部分的多项选择题问卷，并亲手分发给注册胸外科医生。当外科医生的答案符合美国卫生系统药师协会（ASHP）指南时，其答案被视为正确。
邀请了70名胸外科医生参与本研究，他们的回复率为71.4%。35名（70%）外科医生对适当的外科手术抗生素预防有良好的了解。然而，不到一半的受访者了解在对青霉素发生IgE介导反应和革兰氏阴性感染风险情况下的适当外科手术抗生素预防措施。外科医生对制定外科手术抗生素预防的地方和国家指南必要性的态度得分分别为78%和90%。医生在外科手术抗生素预防首次给药时间方面的实践符合ASHP指南，而术中剂量的正确给药符合指南的比例为40%。
尽管胸外科医生对抗生素预防指南态度良好，但他们在正确使用外科手术抗生素预防方面的知识和实践仍需改进。
