含多泡囊乳液神经酰胺的保湿剂：对其在常见皮肤病管理中作用的评估
Multivesicular Emulsion Ceramide-containing Moisturizers: An Evaluation of Their Role in the Management of Common Skin Disorders.
作者信息
Zeichner Joshua A, Del Rosso James Q
机构信息
Department of Dermatology, Mount Sinai Hospital, New York, New York.
出版信息
J Clin Aesthet Dermatol. 2016 Dec;9(12):26-32. Epub 2016 Dec 1.
Abstract
Proper stratum corneum function plays a pivotal role in maintenance of skin health, and improper function leads to skin disease. The stratum corneum is comprised of corneocytes surrounded by intercelluar lipids including ceramides, free fatty acids, and cholesterol. Ceramide predominant moisturizers have become a mainstay of treatment of skin disease. New technologies for delivery of ceramides include multivesicular emulsions, which deposit ceramides in a timerelease manner for a continuous rather than burst effect. Here, the authors review the available data on the use of multivesicular emulsion ceramide moisturizers in various skin diseases.
摘要
角质层的正常功能对维持皮肤健康起着关键作用，而功能异常则会导致皮肤疾病。角质层由被细胞间脂质（包括神经酰胺、游离脂肪酸和胆固醇）包围的角质形成细胞组成。以神经酰胺为主的保湿剂已成为皮肤病治疗的主要手段。神经酰胺递送的新技术包括多泡乳液，其以定时释放的方式沉积神经酰胺，产生持续而非突发的效果。在此，作者综述了多泡乳液神经酰胺保湿剂在各种皮肤病中应用的现有数据。
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