Pettersson C, Gioeli C
Department of Analytical Pharmaceutical Chemistry, University of Uppsala, Sweden.
J Chromatogr. 1987 Jul 10;398:247-54. doi: 10.1016/s0021-9673(01)96510-0.
Acetylquinine chemically bonded to silica was used as a chiral selector in reversed-phase chromatography for the separation of enantiomers of carboxylic acids and amino acid derivatives, e.g., 2-(4-bromophenoxy)propionic acid, warfarin and N-benzoxycarbonylphenylalanine. An organic modifier (methanol) could be used to regulate the retention without significant influence on the stereoselectivity.
键合在硅胶上的乙酰奎宁被用作反相色谱中的手性选择剂，用于分离羧酸和氨基酸衍生物的对映体，例如2-(4-溴苯氧基)丙酸、华法林和N-苄氧羰基苯丙氨酸。可以使用有机改性剂（甲醇）来调节保留时间，而不会对立体选择性产生显著影响。
