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英国波莫纳血清群感染:对农场动物是否构成真正威胁?

serogroup Pomona infections in the UK: is there a real threat for farm animals?

作者信息

Arent Z, Gilmore C, Barlow A M, Smith L, Ellis W A

机构信息

OIE Leptospira Reference Laboratory, Veterinary Sciences Division, Agri-Food and Biosciences Institute, Stoney Road, Stormont, Belfast BT4 3SD, UK.

University Centre of Veterinary Medicine UJ-UR, University of Agriculture in Krakow, Al. Mickiewicza 24/28, Krakow 30-059, Poland.

出版信息

Vet Rec. 2017 Apr 29;180(17):424. doi: 10.1136/vr.103891. Epub 2017 Feb 17.

Abstract

Current typing of strains requires a combination of both serological and molecular methods. Study of the epidemiology of strains within the Pomona serogroup has proved problematic due to the limitations of serological typing methods. This is particularly true of the two main complexes within this group, namely the Pomona, Monjakov, Kennewicki cluster in species and the Mozdok, Tsaratsovo, Kunming, Altodouro cluster in Strains from the south of England have been shown previously to belong to serovar Mozdok, strains of which are maintained by small rodents in western Europe. While they may occasionally cause disease in domestic animals, they are unlikely to be of economic importance. In contrast, serovar Pomona type Kennewicki strains have been shown to be significant animal pathogens, especially in north America, while serovar Pomona types Pomona and Monjakov have not been associated with significant economic loss. The purpose of this study was to examine 10 UK serovar Pomona isolates to assess type as a means of assessing the possible risk they pose to British livestock. All isolates were identified as serovar Pomona type Pomona and were therefore unlikely to pose a significant threat to domestic animals in the UK.

摘要

目前菌株分型需要血清学和分子方法相结合。由于血清学分型方法的局限性,对波莫纳血清群内菌株的流行病学研究已被证明存在问题。在该血清群内的两个主要复合体中尤其如此,即在种内的波莫纳、蒙亚科夫、肯纽维奇聚类,以及在种内的莫兹多克、察拉佐沃、昆明、阿尔托杜罗聚类。先前已表明,来自英格兰南部的菌株属于莫兹多克血清型,西欧的小型啮齿动物可维持该血清型的菌株。虽然它们偶尔可能在家畜中引起疾病,但它们不太可能具有经济重要性。相比之下,已表明肯纽维奇血清型的波莫纳血清型菌株是重要的动物病原体,尤其是在北美,而波莫纳血清型的波莫纳和蒙亚科夫血清型尚未与重大经济损失相关联。本研究的目的是检测10株英国波莫纳血清型分离株,以评估其血清型,作为评估它们对英国家畜可能构成风险的一种手段。所有分离株均被鉴定为波莫纳血清型的波莫纳血清型,因此不太可能对英国的家畜构成重大威胁。

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