Department of Mental Health and Psychiatry, University Hospitals of Geneva, Geneva, Switzerland.
Department of Mental Health and Psychiatry, University Hospitals of Geneva, Geneva, Switzerland.
Psychiatry Res. 2017 May;251:204-211. doi: 10.1016/j.psychres.2017.02.026. Epub 2017 Feb 13.
Child maltreatment (CM) worsens prognosis and quality of life in several psychiatric conditions. Meaning in life is a construct which relates to the sense of purpose that one can perceive in life, and is a key aspect of recovery in psychiatric patients. The lasting impact of CM on meaning in life and its mediating variables have not been studied in patients with chronic persistent psychiatric conditions. One hundred and sixty-six patients with bipolar disorder (N=35), psychotic disorder (N=73), anorexia nervosa (N=30) or borderline personality disorder (N=28) were assessed for meaning in life (revised version of the Life Regard Index (LRI-R)), for CM (Childhood Trauma Questionnaire (CTQ)) and for internalized/externalized psychopathology. CM was associated with a lower LRI score. Structural Equation Modeling showed that internalized psychopathology (depression, hopelessness and low self-esteem) was the main mediator of the impact of CM on meaning in life. The direct effect of CM on meaning in life was not significant. Having suffered from negligence or abuse during childhood is associated with lower meaning in life in adults with persistent and pervasive psychiatric disorders. Treating depressive symptoms and improving self-esteem may improve meaning in life in patients with severe mental disorders who were affected by CM.
儿童虐待(CM)会恶化几种精神疾病的预后和生活质量。生活意义是一个与一个人在生活中感知到的目标感相关的结构,是精神疾病患者康复的关键方面。CM 对生活意义及其中介变量的持久影响在慢性持续性精神疾病患者中尚未得到研究。166 名双相情感障碍(N=35)、精神病性障碍(N=73)、神经性厌食症(N=30)或边缘型人格障碍(N=28)患者接受了生活意义(生活观量表修订版(LRI-R))、CM(儿童期创伤问卷(CTQ))和内化/外化精神病理学评估。CM 与较低的 LRI 评分相关。结构方程模型显示,内化的精神病理学(抑郁、绝望和低自尊)是 CM 对生活意义影响的主要中介因素。CM 对生活意义的直接影响不显著。在患有持续性和普遍性精神障碍的成年患者中,童年时期遭受忽视或虐待与较低的生活意义有关。治疗抑郁症状和提高自尊心可能会改善受 CM 影响的严重精神障碍患者的生活意义。