Cohrs Austin C, Leslie Douglas L
Center for Applied Studies in Health Economics (CASHE), Department of Public Health Sciences, Penn State College of Medicine, Pennsylvania State University, 90 Hope Drive, Suite 2200, Hershey, PA, 17033, USA.
J Autism Dev Disord. 2017 May;47(5):1416-1422. doi: 10.1007/s10803-017-3063-y.
Previous studies showing that Autism Spectrum Disorder (ASD) in children can have secondary effects on the child's parents are limited by small sample sizes and parent self-report. We examined the odds of depression in parents of children with ASD compared to parents of children without ASD using a large national claims database. Mothers (OR 2.95, 95% CI 2.81-3.09) and fathers (OR 2.41, 95% CI 2.25-2.58) of children with ASD were more likely to have a diagnosis of depression than parents of children without ASD. Odds of depression also increased when there was more than one child with ASD in the family and with child age. Study results reinforce the benefits of support and education for parents of children with ASD.
以往研究表明，儿童自闭症谱系障碍（ASD）会对患儿父母产生继发性影响，但这些研究因样本量小和采用父母自我报告而受到限制。我们使用一个大型国家索赔数据库，比较了患有ASD儿童的父母与未患ASD儿童的父母患抑郁症的几率。患有ASD儿童的母亲（比值比2.95，95%置信区间2.81 - 3.09）和父亲（比值比2.41，95%置信区间2.25 - 2.58）比未患ASD儿童的父母更有可能被诊断为抑郁症。当家庭中有不止一个患有ASD的孩子以及孩子年龄增长时，患抑郁症的几率也会增加。研究结果强化了为患有ASD儿童的父母提供支持和教育的益处。
